Histidine is a nutritionally essential amino acid precursor for several hormones (eg, thyrotropin-releasing hormone) and critical metabolites affecting renal function, neurotransmission, gastric secretion, and the immune system. Histidine's unique acid/base properties make it a versatile catalytic residue in many enzymes and for those proteins and enzymes that coordinate metal ions.[1]| www.ncbi.nlm.nih.gov
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