Objectives To identify and critically appraise published clinical practice guidelines (CPGs) regarding healthcare of gender minority/trans people. Design Systematic review and quality appraisal using AGREE II (Appraisal of Guidelines for Research and Evaluation tool), including stakeholder domain prioritisation. Setting Six databases and six CPG websites were searched, and international key opinion leaders approached. Participants CPGs relating to adults and/or children who are gender minorit...| BMJ Open