Learn about the history of sickle cell disease in the United States, from its discovery in 1910 to the NHLBI legacy of research that has advanced the understanding of sickle cell disease, improved clinical progress, and paved the way for widely available cures.| NHLBI, NIH
Treatment options for sickle cell disease include medicines that lessen symptoms, blood transfusions, blood and bone marrow transplants, and gene therapy treatments. Bone marrow transplants and gene therapies are potential cures for some people.| NHLBI, NIH
Symptoms vary depending on the individual, but they may include jaundice, tiredness, and painful swelling of the hands and feet. Serious symptoms needing medical attention include serious anemia, fever, acute chest syndrome, stroke, pain crises, and prolonged erections. Some symptoms are linked with other medical and social factors.| NHLBI, NIH
People with sickle cell trait carry only one copy of the sickle hemoglobin gene and rarely have any symptoms of sickle cell disease. However, in rare instances, some people who have sickle cell trait can experience medical complications.| NHLBI, NIH
Living with sickle cell disease involves receiving routine follow-up care, learning to manage a pain crisis, adopting a healthy lifestyle, and preventing health problems for yourself or your child.| NHLBI, NIH
Sickle cell disease can cause pain, infections, and joint problems throughout the body. It can also lead to severe anemia and complications in specific body parts.| NHLBI, NIH
Anemia is a common condition that occurs when your blood has a lower-than-normal amount of red blood cells or hemoglobin. Anemia can be inherited or acquired. Learn about the causes, symptoms, and treatments for anemia.| NHLBI, NIH
Lovotibeglogene autotemcel Injection: learn about side effects, dosage, special precautions, and more on MedlinePlus| medlineplus.gov
Exagamglogene autotemcel: learn about side effects, dosage, special precautions, and more on MedlinePlus| medlineplus.gov
Learn what a stroke is, including the two types of stroke. Know the immediate steps to take in a medical emergency.| NHLBI, NIH