Symptoms vary depending on the individual, but they may include jaundice, tiredness, and painful swelling of the hands and feet. Serious symptoms needing medical attention include serious anemia, fever, acute chest syndrome, stroke, pain crises, and prolonged erections. Some symptoms are linked with other medical and social factors.| NHLBI, NIH
People with sickle cell trait carry only one copy of the sickle hemoglobin gene and rarely have any symptoms of sickle cell disease. However, in rare instances, some people who have sickle cell trait can experience medical complications.| NHLBI, NIH
Sickle cell disease can cause pain, infections, and joint problems throughout the body. It can also lead to severe anemia and complications in specific body parts.| NHLBI, NIH
Anemia is a common condition that occurs when your blood has a lower-than-normal amount of red blood cells or hemoglobin. Anemia can be inherited or acquired. Learn about the causes, symptoms, and treatments for anemia.| NHLBI, NIH
Learn what a stroke is, including the two types of stroke. Know the immediate steps to take in a medical emergency.| NHLBI, NIH
