Ewing sarcoma (EwS) is a rare and aggressive malignancy, which frequently affects children. One of the few recurrent genomic variants in EwS is genomic copy number deletion of CDKN2A; however, the clinical consequences of dysregulation of CDKN2A in EwS are unclear. In this study, we revisit CDKN2A t …| PubMed
The catchment area is characterized by disproportionately higher cancer incidence and mortality rates than other regions in Florida. These disparities are evident in medically underserved populations, which include rural populations (16 out of 23 counties are rural), more than a quarter of racial/ethnic minority residents (26% underrepresented minorities, 16% of which are non-Hispanic Black and…| Cancer Center
This research is done by engaging key cancer pathways and identifying and developing novel biomarkers, assays and methods for rapid agent selection and clinical translation as part of precision oncology approaches. The program engages members of all four UF Health Cancer Center programs. It is implemented by disease group-focused mini-retreats, program meetings and IIT Think Tank (i2T3)-mediated structured facilitation of the translation of discoveries ranging from high-throughpu...| Cancer Center