Spontaneous abortion or miscarriage is defined as the loss of pregnancy less than 20 weeks gestation. The American College of Obstetricians and Gynecologists (ACOG) estimates it is the most common form of pregnancy loss. It is estimated that as many as 26% of all pregnancies end in miscarriage and up to 10% of clinically recognized pregnancies.[1][2] [3] Moreover, 80% of early pregnancy loss occurs in the first trimester. [1][2] The risk of miscarriage decreases after 12 weeks gestation.| www.ncbi.nlm.nih.gov