Tenecteplase (TNK) is a single-bolus recombinant fibrinolytic agent used to manage intravascular clots. The drug is in the tissue plasminogen activator (tPA) class of medications. FDA-approved indications include acute ST-elevation myocardial infarction (STEMI). Tenecteplase is the thrombolytic agen …| PubMed
Tissue plasminogen activator (tPA) is classified as a serine protease (enzymes that cleave peptide bonds in proteins). It is thus one of the essential components of the dissolution of blood clots. Its primary function includes catalyzing the conversion of plasminogen to plasmin, the primary enzyme i …| PubMed