Sickle cell disease is an inherited blood disorder that affects hemoglobin, the protein that carries oxygen through the body. Misshapen red blood cells can block blood flow causing lifelong health problems. The only cure is a blood and bone marrow transplant, but treatments are available to manage the condition.| NHLBI, NIH
Research on CAR T-cell therapy is progressing rapidly to improve the cancer treatment, expand its use to more cancers, and better manage its side effects.| www.cancer.gov
The FDA approved the first cell-based gene therapies, Casgevy and Lyfgenia, for the treatment of sickle cell disease in patients 12 years and older.| U.S. Food and Drug Administration