A vast amount of expert knowledge currently remains inaccessible to digital information systems. Expert knowledge elicitation is a systematic approach to accessing and synthesizing the insights of subject matter experts, especially when available objective data are incomplete. In plant pathology, expert knowledge elicitation is valuable for addressing urgent, uncertain, and/or future challenges, such as emerging disease threats, complex epidemiological systems, knowledge gaps when resources a...| Emerging Pathogens Institute » University of Florida
With her stipend offered by the UF Emerging Pathogens Institute, this undergraduate student traveled to Italy to shadow in a teaching hospital.| Emerging Pathogens Institute » University of Florida
Why have there been so many recent outbreaks of food-borne illnesses? Food-safety experts are increasingly concerned about pathogens such as Salmonella, E. coli and Listeria.| epi.ufl.edu
The human microbiome plays a critical role in health and disease. Disruptions in microbiota composition or function have been implicated not only as markers but also as drivers of diverse pathologies, creating opportunities for targeted microbiome interventions. Advancing these therapies requires experimental models that can unravel the complex, bidirectional interactions between human tissue and microbial communities.| Emerging Pathogens Institute » University of Florida
The rise of antibiotic-resistant bacterial pathogens poses a critical global health challenge, necessitating innovative therapeutic strategies. This study explores host-targeted therapies by focusing on deubiquitinating enzymes (DUBs), key regulators of the ubiquitin-proteasome system (UPS) that mediate host-pathogen interactions. Using Salmonella-infected macrophages, we screened a UPS-targeted compound library and identified several compounds that enhanced bacterial clearance without affect...| Emerging Pathogens Institute » University of Florida
