How fast should we correct severe hyponatremia? Observational data shows an association between slower and more death.| First10EM
A look at two trials (PARAMEDIC3 and IVIO) comparing intraosseous (IO) and intravenous (IV) access in out of hospital cardiac arrest.| First10EM
A critical appraisal of the TRAIN trial - conservative versus liberal transfusion in brain injury, short on the heels of HEMOTION| First10EM
A critical appraisal of the HEMOTION trial - a multicenter RCT comparing liberal and restrictive blood transfusion in traumatic brain injury.| First10EM
A critical appraisal of Nielsen 2024, which demonstrates that oral antibiotics are noninferior to IV in pediatric bone and joint infections.| First10EM
A critical appraisal of the COSTED trial: A multi center RCT looking at smoking cessation in the emergency department| First10EM
Gestalt is better than decision rules for identifying sepsis in the emergency department (obviously, to anyone who reads EBM)| First10EM
A simplified guide to critical appraisal. Evidence based medicine is really easy!| First10EM
A critical appraisal of the PREOXI trial, a multicenter RCT that remonstrates reduced peri-intubation hypoxia with NIPPV| First10EM
Andexanet alfa: there was no reason to use this drug until now, and nothing changes with this first RCT. Harmful and expensive.| First10EM
A critical appraisal of a meta-analysis looking at MRI in first episode psychosis. Despite the conclusions, routine MRI is not warranted.| First10EM