Reduced production of orexin, a signaling molecule, is associated with problems in sleep-wake cycles in Rett syndrome mice, a study found.| Rett Syndrome News
Cannabidivarin preserved cognitive function and improved motor coordination in a female mouse model of Rett syndrome, a study suggests.| Rett Syndrome News
The Clinical Severity Scale (CSS) includes 13 items, with a total score ranging from 0 to 58, higher scores indicating more disease severity.| Rett Syndrome News
A lack of awareness in the medical community about Rett syndrome in males commonly leads to misdiagnoses or diagnostic delays, a study found.| Rett Syndrome News
Neurogene received clearance from the FDA for a pivotal trial of NGN-401, which could support an application for the gene therapy's approval.| Rett Syndrome News
The brain’s electrical activity in response to sound may serve as a biomarker for Rett treatment response, per a study.| Rett Syndrome News
Taysha Gene Therapies announced details for the second part of a clinical trial testing Rett gene therapy TSHA-102.| Rett Syndrome News
The first four Rett syndrome patients treated with the gene therapy candidate NGN-401 have seen meaningful gains in skills, data show.| Rett Syndrome News
Low-dose treatment with shock wave therapy for three months was seen to ease spasticity and improve motor function in Rett syndrome children.| Rett Syndrome News
NGN-401 is one of six picked, three each by the Center for Biologics Evaluation and Research, and the Center for Drug Evaluation and Research.| Rett Syndrome News
A brain surgery called corpus callosotomy reduced seizure burden in a young girl with Rett syndrome and hard-to-treat seizures, per a report.| Rett Syndrome News
The US regulatory agency acts to support the potential gene therapy's development, with ongoing Phase 1/2 trial showing safety in patients.| Rett Syndrome News
ADH-503, a possible cancer therapy affecting immune cell activity, slowed progression and prolonged survival in a Rett syndrome mouse model.| Rett Syndrome News
Long-term treatment with Daybue (trofinetide) led to continual improvements in symptoms in people with Rett syndrome in extension studies, data show.| Rett Syndrome News
The International Rett Syndrome Foundation designated three new centers of excellence for clinical care of Rett patients.| Rett Syndrome News
Work in a Rett cell model found the potential gold nanocrystal therapy significantly improved mitochondrial function and neuronal health.| Rett Syndrome News
Learn more about the rare neurodevelopmental disorder Rett syndrome, including its causes, symptoms, diagnosis and treatment.| Rett Syndrome News