People with sickle cell trait carry only one copy of the sickle hemoglobin gene and rarely have any symptoms of sickle cell disease. However, in rare instances, some people who have sickle cell trait can experience medical complications.| NHLBI, NIH
Sickle cell disease can cause pain, infections, and joint problems throughout the body. It can also lead to severe anemia and complications in specific body parts.| NHLBI, NIH