Sickle cell disease can affect reproductive and sexual health of men and women. Men can have priapism (an erection lasting 4 or more hours), which can lead to sexual problems. Women face high-risk pregnancies, which could also worsen sickle cell symptoms.| NHLBI, NIH
Sickle cell disease can cause pain, infections, and joint problems throughout the body. It can also lead to severe anemia and complications in specific body parts.| NHLBI, NIH