Sickle cell disease can affect reproductive and sexual health of men and women. Men can have priapism (an erection lasting 4 or more hours), which can lead to sexual problems. Women face high-risk pregnancies, which could also worsen sickle cell symptoms.| NHLBI, NIH
Symptoms vary depending on the individual, but they may include jaundice, tiredness, and painful swelling of the hands and feet. Serious symptoms needing medical attention include serious anemia, fever, acute chest syndrome, stroke, pain crises, and prolonged erections. Some symptoms are linked with other medical and social factors.| NHLBI, NIH
Sickle cell disease can cause pain, infections, and joint problems throughout the body. It can also lead to severe anemia and complications in specific body parts.| NHLBI, NIH
