The AlphaFold Protein Structure Database (AFDB) has redesigned its entry pages to make exploring predicted protein structures faster, clearer, and more intuitive. This update delivers a streamlined experience across devices, whether you’re browsing from the lab, your desktop, or on the move.…| EMBL
Maria Costanzo, former predoc at EMBL Barcelona, talks about YAP, her favourite protein in the shape of a heart.| EMBL
Just over a week ago the long-awaited AlphaFold2 (AF2) method paper and associated code finally came out, putting to rest questions that I and many others raised about public disclosure of AF2. Already, the code is being pushed in all sorts of interesting ways, and three days ago the companion paper and database were published, where … Continue reading →| Some Thoughts on a Mysterious Universe
The past week was a momentous occasion for protein structure prediction, structural biology at large, and in due time, may prove to be so for the whole of life sciences. CASP14, the conference for …| Some Thoughts on a Mysterious Universe
But it may well be semi-supervised. For some time now I have thought that building a latent representation of protein sequence space is a really good idea, both because we have far more sequences than any form of labelled data, and because, once built, such a representation can inform a broad range of downstream tasks. … Continue reading →| Some Thoughts on a Mysterious Universe
For over a decade now I have been working, essentially off the grid, on protein folding. I started thinking about the problem during my undergraduate years and actively working on it from the very beginning of grad school. For about four years, during the late 2000s, I pursued a radically different approach (to what was … Continue reading →| Some Thoughts on a Mysterious Universe