Unlocking the Power of Live-Cell Kinetics in Degrader Development - Promega Connections
Incorporating live-cell kinetic analysis helps answer questions about how fast, how thoroughly and how sustainably a degrader works| Promega Connections
The blog discusses the importance of selectivity in drug development and chemical probe use. It highlights advancements in cellular profiling techniques, like chemical proteomics and CETSA-MS, which provide more accurate insights into compound-target interactions. These methods enhance understanding of drug selectivity, enabling identification of novel off-targets and improving therapeutic opportunities. The post Cellular Selectivity Profiling: Unveiling Novel Interactions and More Accurate C...| Promega Connections
Incorporating live-cell kinetic analysis helps answer questions about how fast, how thoroughly and how sustainably a degrader works| Promega Connections
This guest blog post is written by Tian Yang, Associate Product Manager at Promega. There are often challenges with translating results from a test tube into a living system, demanding more physiologically relevant assays. In drug discovery, demonstrating a compound’s ability to modulate its target protein in live cells is a critical step in the […]| Promega Connections
