Unlocking the Power of Live-Cell Kinetics in Degrader Development - Promega Connections
Incorporating live-cell kinetic analysis helps answer questions about how fast, how thoroughly and how sustainably a degrader works| Promega Connections
Targeted protein degradation (TPD) is an emerging drug discovery strategy that offers an entirely different approach to tackle disease-relevant proteins, including classic “undruggable” targets. Instead of inhibiting protein function, small molecules like PROTACs and molecular glues co-opt the cell’s own ubiquitin-proteasome system to eliminate specific proteins altogether. But as this targeted approach gains traction, it also […] The post A New View of Protein Degradation with HiBiT...| Promega Connections
Incorporating live-cell kinetic analysis helps answer questions about how fast, how thoroughly and how sustainably a degrader works| Promega Connections
