A 2025 study retrospectively reviewed histopathology slides from 20 trans-identifying females (ages 16–35) who underwent “gender-affirming” gynecologic surgery following 4–63 months of testosterone therapy (mean duration 21.7 ± 17.8 months). Key findings included: A comparison group of 25 benign hysterectomy samples from females of reproductive age showed no transitional or prostatic-type metaplasia, and only 2 cases (8%) […] The post Testosterone induces distinct cellular chan...| Stats for Gender
Complete guide to bottom growth on testosterone for trans men. Learn timelines, what to expect, care tips & FAQs. Expert advice from GenderGP| GenderGP
A 2025 systematic review and meta-analysis of 29 studies (28 included in meta-analysis) involving 2,674 individuals found that “gender-affirming” hormone therapy led to statistically significant body mass index (BMI) increases. The mean age across studies ranged from 16 to 56 years, and no prior puberty suppression was reported before the initiation of GAHT. The researchers […]| Stats for Gender
Learn how vitamin D impacts testosterone levels, including the latest research, how to take it, how much to use, and which forms are best.| Male Health Review
In a 2022 study1 published in the Journal of Sexual Medicine, researchers analyzed 70.3 million electronic health records from 46 healthcare organizations to examine mental health outcomes in men using testosterone therapy. The study compared 263,579 men who used testosterone to over 17.8 million men who did not. Results showed testosterone use was independently associated […] The post Testosterone therapy is associated with nearly doubled depression risk and 52% higher suicide attempt rate...| Stats for Gender
Did you know? Low libido in both women and men can be caused by thyroid issues. Learn more about low libido and Hashimoto's. Both can be reversed!| Dr. Izabella Wentz, PharmD
In a 2025 study in the Journal of Clinical Investigation1, females taking testosterone for gender transition showed biological changes consistent with subclinical kidney stress and tubular injury after three months—including a 134% increase in a urinary marker linked to kidney inflammation (YKL-40) and an 8% rise in an inflammatory blood protein (TNF receptor-1). Although overall […] The post Testosterone use in females triggers biological signs of kidney stress and injury within just thr...| Stats for Gender
Nava Health experts explain that testosterone plays a critical role in a woman’s overall well-being, especially during perimenopause and menopause.| Nava Health
A 2025 study from Argentina found that 26.6% of female adults presenting for “gender-affirming hormone therapy” had polycystic ovary syndrome (PCOS) prior to starting any hormonal treatment. PCOS is a hormonal disorder characterized by irregular periods, excess male hormone levels, and cysts on the ovaries. This rate is 2-3 times higher than the 8-13% prevalence […] The post Polycystic ovary syndrome (PCOS) is more prevalent in females seeking medical transition. appeared first on Stats...| Stats for Gender
The frequency and duration of testosterone shortages have been on the rise globally for the last decade. If you think this couldn't happen to you, then you haven't been paying attention. This investigative report will help you get informed so that you know what to do when a testosterone shortage hits your area. The post Testosterone Shortages: Whatcha Gonna Do When They Come For YOU? appeared first on TransGuys.com.| TransGuys.com
Learn how aging affects testosterone levels and discover simple tips to boost muscle, mood, and energy naturally.| Andro HQ
Dealing with the effects of low testosterone? Here are some effective ways to naturally promote testosterone levels with foods & supplements…| BrainMD Blog
Testosterone Replacement Therapy (TRT) has garnered considerable attention in the medical community. While discussions often focus on its benefits for sexual health and energy levels, ample research has highlighted its benefits for cardiovascular health. That might be surprising since there are many rumors claiming that TRT increases the risk of cardiovascular events, like heart attacks… The post The TRAVERSE Trial Dispels Myths Surrounding Testosterone Replacement Therapy (TRT) appeared fi...| Testosterone Centers of Texas
Many men are stuck with a lower quality of life due to the underdiagnosis of Low Testosterone—learn more.| Testosterone Centers of Texas
If you've ever worried about the possible long-term effects of being on Testosterone, you can relax because science has your back.| TransGuys.com
Adapted from a chapter in my recent book, The Great Feminization…| thoughtsofstone.github.io