This week on Entanglements, our hosts ask: Should we run outdoor geoengineering experiments? Intentionally altering the planet’s climate has been fiercely debated for years. And although some scientists are increasingly open to the idea, there is still disagreement on whether or not to move forward.| Undark Magazine
The HHS secretary promised to identify the causes of autism with a new $50 million research initiative. But RFK Jr. has also taken aim at the traditional scientific approach to autism, stripping funding from more than 50 autism-related studies and shutting down a federal research lab that has been answering the very questions he has been asking.| Undark Magazine
Many insurance policies don’t cover GLP-1s for weight loss because the drugs don’t yet have a clear track record of long-term success. But lack of insurance coverage can cause people to quit their meds prematurely, creating a vicious circle. Could a more holistic approach to treatment help?| Undark Magazine
This week on Entanglements, our hosts speak with Jill Escher, a philanthropist, president of the National Council on Severe Autism, and parent of two young adults with severe nonverbal autism, and Eric García, the Washington bureau chief at The Independent, who himself is autistic.| Undark Magazine
Amid the measles outbreak in Texas early this year, the Trump administration’s actions sowed fear and confusion among CDC scientists that kept them from performing the agency’s most critical function — emergency response — when it mattered most, an investigation from KFF Health News shows.| Undark Magazine
Climate scientists use a special kind of simulation, called Earth system models to help grasp the planet’s past and predict its future. But as part of Trump’s proposed budget and programmatic cuts, ESMs are now under threat — including a DOE initiative that has received more than a decade of investment.| Undark Magazine
A study using massive biobank databases has revealed associations between gastrointestinal tract disorders and the neurodegenerative diseases Alzheimer’s and Parkinson’s, and has characterized their genetic and proteomic links. The post Gut Disorders Linked with Alzheimer’s and Parkinson’s Neurodegeneration appeared first on Inside Precision Medicine.| Inside Precision Medicine
Transdermal estradiol, (E2) given with either patches or gels, was associated with better memory of words or events, while oral administration of estradiol was linked with improved prospective memory, or remembering to do things in the future. The post Estradiol Delivery Method Tied to Memory Differences After Menopause appeared first on Inside Precision Medicine.| Inside Precision Medicine
A biomarker present in 20% of ER+/HER2− breast cancers has been identified, with potential to predict heightened sensitivity to CDK4/6 inhibitor drugs. The post Biomarker Discovery Could Improve Personalized Care in ER+ Breast Cancer appeared first on Inside Precision Medicine.| Inside Precision Medicine
A first-in-human trial testing a novel allogeneic synthetic TCR and antigen receptor (STAR) T cell therapy has shown encouraging early results in patients with severe, treatment-resistant systemic lupus erythematosus (SLE). The post STAR T, An Allogeneic CAR T Alternative, Is Effective in Lupus Patients appeared first on Inside Precision Medicine.| Inside Precision Medicine
Measuring acoustic emissions from microbubbles during focused ultrasound may help researchers standardize blood-brain barrier opening during glioma treatment. The post Glioma Treatment May Benefit from Acoustic Biomarker–Guided BBB Opening appeared first on Inside Precision Medicine.| Inside Precision Medicine
Tamoxifen fuels uterine cancer by activating the PI3K pathway, according to a new study, bypassing mutations normally required. Findings point to potential strategies to reduce risk while preserving the drug’s breast cancer benefits. The post How Tamoxifen Raises Uterine Cancer Risk—and a Path to Prevention appeared first on Inside Precision Medicine.| Inside Precision Medicine
Triple-negative breast cancer in this population was largely similar to that of Asian American and non-Hispanic white women. The post Triple-Negative Breast Cancer Mutations Mapped in Black Women appeared first on Inside Precision Medicine.| Inside Precision Medicine
The research used CRISPR/Cas9 to develop an in vivo screen of MYC-driven lymphoma in mouse models to show that the loss of NPRL3, DEPDC5, or NPRL2 in the GATOR1 complex significantly accelerates lymphoma development. The post CRISPR Screen Identifies GATOR1 as Lymphoma Tumor Suppressor appeared first on Inside Precision Medicine.| Inside Precision Medicine
Implanting donor heart valves in children with congenital heart disease can be safe and effective and reduces the number of operations children need as they grow, research shows. The post Transplanting Heart Valves Effective Option for Congenital Heart Disease appeared first on Inside Precision Medicine.| Inside Precision Medicine
PGT-A for women 35 to 42, a group that has a higher risk of producing embryos with chromosomal abnormalities, could improve IVF success.| Inside Precision Medicine
The state is at the forefront of changes to vaccination policy — and for public health more broadly. What does that frontier look like?| Undark Magazine
To date, NASA has allocated more than $26 billion in government property to contractors in support of six Artemis programs. Today, the NASA Office of Inspector General (OIG) released a memorandum examining how the Agency is managing this significant investment. The Artemis campaign aims to return humans to the Moon and establish a sustainable lunar […]| NASA OIG
Today, the NASA Office of Inspector General issued a new audit examining the Agency’s Standing Review Board (SRB) process, which provides independent assessments of programs and projects to improve performance and reduce risk. SRBs are a vital component of NASA’s system of checks and balances to enhance transparency, accountability, and cooperation. They are composed of […]| NASA OIG
Teal Health has announced the launch of their Teal Wand at-home cervical cancer screening kit and virtual telehealth services in California.| Inside Precision Medicine
The device detects infection via temperature, pH, and inflammation markers such as C-reactive protein (CRP) and interleukin-6 (IL-6).| Inside Precision Medicine
As people turn to AI for therapy and companionship, some say the models still need to learn the nuances of human humor.| Undark Magazine
To propel Americans to the Moon and beyond, NASA has made significant investments that fuel innovation here on Earth. Each year, the Agency offers grants and cooperative agreements that support research at institutions across the United States. In order to maintain the nation’s competitive advantage and protect national security, federal law prohibits these grant recipients […]| NASA OIG
Glipizide, a widely prescribed drug for type II diabetes, can increase the five-year risk of major cardiovascular events by 13%.| Inside Precision Medicine
New research shows how glioblastoma cells infiltrate the brain and which key genes drive the invasion, paving the way to new treatments.| Inside Precision Medicine
A new mRNA cancer vaccine, in combination with common immunotherapy drugs, could become the first universal cancer vaccine.| Inside Precision Medicine
AI model outperforms cardiologists in detecting hidden structural heart disease from routine ECGs, advancing early screening.| Inside Precision Medicine
The allogeneic Azer-cel showed impressive response rates in a Phase Ib study with DLBCL patients who had failed autologous CAR T cell therapy treatments.| Inside Precision Medicine
Cancer deaths linked to obesity have tripled in the U.S. over the past two decades, according to a study presented Sunday at ENDO.| Inside Precision Medicine
Mapping blood stem cell metabolism reveals choline as a key nutrient to preserve stem cell health and guide precision therapies.| Inside Precision Medicine
Long-term obesity may trigger aging molecular signals in young adults including epigenetic modifications and telomere shortening, researchers have discovered.| Inside Precision Medicine
As the U.S. and other countries cut funding for global health initiatives, what role will philanthropy take?| Undark Magazine
After a multi-year fight against former President Joe Biden’s energy, climate and environmental policies, Montana Attorney General Austin Knudsen has corralled 18 other Republican attorneys general to back President Donald Trump and his energy policies. Knudsen, who has led the Montana Department of Justice since 2021, is attempting to enter the judicial ring in a […]| Flathead Beacon
Kalispell Where: 115 Stryker Peak Tr. Price: $630,000 What: Three-bedroom, two-bath home Square Feet: 1,657 This lovely home sits on a large corner lot and features a bright and open floorplan, vaulted ceilings, stainless steel appliances, granite counters, and a large island. Outside is a covered patio, fenced backyard, fire pit and underground sprinklers. […]| Flathead Beacon
Kalispell city officials are gathering residents’ thoughts on a new land use plan that will determine how city land is developed over the next 20 years, a change to growth policy mandated by the Montana Land Use Plan Act (MLUPA) that lawmakers passed during the 2023 legislative session. Land use policies dictate how land can […]| Flathead Beacon
The captured infantry fighting vehicle has had its Bushmaster chain gun swapped out for a Russian-made weapon. The captured infantry fighting vehicle has had its Bushmaster chain gun swapped out for a Russian-made weapon.| The War Zone
A funding pause at the University of Michigan illustrates the uncertainty around new language in NIH grant awards.| Undark Magazine
Researchers have long advocated for a more systematic approach to environmental health, but funding may not hold.| Undark Magazine
Pat Williams, Montana’s longest-serving member of the U.S. House, died Wednesday evening in a Missoula hospital. The Butte native, who was Montana’s last Democrat elected to the House, served nine terms from 1979 to 1997, including two as the state’s at-large representative. Williams was 87. “He was a hard-nosed politician but he had such a […]| Flathead Beacon
Israel is declaring some progress in rolling back Iran’s long-range ballistic missile capabilities, but these weapons remain a major threat. Israel is declaring some progress in rolling back Iran’s long-range ballistic missile capabilities, but these weapons remain a major threat.| The War Zone
Roslindale can now build bigger and higher thanks to the passage of new zoning through Boston's Squares + Streets.| The Scope
Israel’s strikes on Tehran are now accelerating after achieving air superiority over the capital, with an eye towards Iran’s east. Israel’s strikes on Tehran are now accelerating after achieving air superiority over the capital, with an eye towards Iran’s east.| The War Zone
Department of Homeland Security is using its most powerful and persistent eyes in the sky as part of its response to the unrest in Los Angeles.| The War Zone
BILLINGS – President Donald Trump on Thursday ordered government officials to consolidate wildland firefighting into a single program, despite warnings from former federal officials that it could be costly and increase the risk of catastrophic blazes. The order aims to centralize firefighting efforts now split among five agencies and two Cabinet departments. Trump’s proposed budget for next year calls […]| Flathead Beacon
Attorneys for BNSF Railway, the U.S. government and a Libby asbestos-screening clinic sparred in federal court Thursday over how the railroad giant can collect a multimillion-dollar judgment stemming from hundreds of fraudulent diagnoses made by the nonprofit health care clinic, a case litigated extensively in a 2023 jury trial. The prior legal battle left the […]| Flathead Beacon
The budget reconciliation bill is a sweeping piece of legislation, part of which aims to reduce or increase spending for several federal programs. Federal programs affected, should the bill pass, include Medicaid.| Flathead Beacon
Mossad operatives went as far as setting up drone and missile bases near major air defense sites and other key targets. Mossad operatives went as far as setting up drone and missile bases near major air defense sites and other key targets.| The War Zone
The AI agent known as Centaur demonstrated its value in beyond-visual-range combat, including providing the pilot with missile firing cues. The AI agent known as Centaur demonstrated its value in simulated beyond-visual-range combat, including providing the pilot with missile firing cues.| The War Zone
Some of the bombers were armed with cruise missiles when Ukraine’s drones rained down on them. Some of the bombers were armed with cruise missiles when Ukraine’s drones rained down on them.| The War Zone
A proposed U.S. Fish and Wildlife Service rule would allow activities that harm the habitats of protected species.| Undark Magazine
The issue of Flathead Lake’s water levels has entered the state legislature with a resolution to treat recreation on par with the rest of the water’s various uses. Senate Joint Resolution 18 requests that decision-making bodies who oversee the lake’s water levels “ensure that recreation needs be measured fairly compared to hydropower, fish, and irrigation […]| Flathead Beacon
U.S. airpower is flowing to the Indian Ocean outpost as threats to Iran escalate and the bombing campaign against the Houthis grinds on.| The War Zone
The White House put out a stark warning to Iran and said strikes against the Houthis will only stop if their attacks on ships end.| The War Zone
Despite 18 months of attacks by the Houthis, the U.S. does not have a clear idea of how many standoff weapons they possess or how they get all of them.| The War Zone
USAF analyses show a need for aircraft that can persist in contested areas and that standoff capabilities alone can't win future fights.| The War Zone
For many, the quest for flawless skin remains at the top of our beauty wish lists, and thanks to the surge in popularity of non-invasive aesthetic treatments such as laser skin resurfacing, achieving a radiant complexion has never been more accessible. Offering safe, precise and long-lasting results for a variety of concerns, many are opting […]| The Upcoming
New research published by Virgin StartUp shows that over a quarter (26%) of 18-24-year-olds are gearing up to start their own businesses in 2025.| ByteStart
In celebration of a decade since the release of their critically acclaimed third album, Darling Arithmetic, Villagers, led by Conor O’Brien, are scheduled to perform a series of special acoustic shows. The performances are planned for late May in three major European cities: London, Dublin and Paris. Darling Arithmetic, which debuted in April 2015, quickly climbed […]| The Upcoming
For George Ostrom, the word “bored” didn’t exist. Between smoke jumping into the Bob Marshall Wilderness, greeting the Flathead Valley every morning as a KOFI radio announcer, starring as Richard Widmark’s stuntman in adventure film “Red Skies of Montana,” erecting the largest weekly newspaper in Montana, chasing down grizzly bear stories, helping compose the Wilderness […]| Flathead Beacon
If you make some extra money via a 'side hustle' - by selling online - you should be aware that digital platforms now share information about sellers with HMRC. You might need to pay tax on any profits you make - but it depends!| ByteStart
MUBI has confirmed the UK theatrical release of September Says, the first directorial venture by Ariane Labed. The film is scheduled to debut in cinemas across the United Kingdom on 21st February 2025. This announcement follows the film’s world premiere at the 2024 Cannes Film Festival, where it was featured in the Un Certain Regard […]| The Upcoming
The much-anticipated documentary Becoming Led Zeppelin, which explores the origin and rapid ascent of the legendary rock band, is set to premiere in IMAX on 5th and 6th February 2024, followed by a wider release in cinemas from 7th February. Directed by Bernard MacMahon, the feature offers an unprecedented look at Led Zeppelin’s formative years, featuring […]| The Upcoming
Netflix is scheduled to premiere its latest film, The Electric State, on 14th March 2025. Directed by Anthony and Joe Russo, known for their work on Avengers: Endgame, the film features a star-studded cast including Millie Bobby Brown, Chris Pratt and Academy Award winner Ke Huy Quan. The narrative unfolds in an alternate retro-futuristic version of […]| The Upcoming
With less than 10 days to Christmas, the festive countdown is well and truly underway. But don’t worry, there’s no need to start panic buying just yet as we’ve rounded up the ultimate last-minute Christmas gift guide, full of thoughtful presents for her. From beautiful gift sets to page-turning reads, here’s the top picks to […]| The Upcoming
With Russia's resources being poured into its war in Ukraine, defending its naval base and airfield in Syria would be more of a challenge than three years ago.| The War Zone
We also now know the drone incursions last week happened over multiple bases, not just RAF Lakenheath.| The War Zone
Blending his Sri Lankan heritage and modern mixology, Ryan Chetiyawardana, Mr Lyan, introduces a new range of cocktail seasonings in 2025. Dubbed Three Families, the collection is a collaboration with three Sri Lankan families, each with deep roots in the beverage industry. The seasonings, encapsulating the tropical essence of Sri Lanka, will be available in […]| The Upcoming
The autumn budget was one of the most anticipated in recent memory. Employers National Insurance is set to rise from April 2025, with inreases to CGT (including BADR) and other taxes. Read the key points here.| ByteStart
Following a decennial redistricting process that reshaped Montana’s legislative districts, Democrats picked up an additional state legislative seat in Flathead County, which remains deeply Republican. Republicans won two of three state Senate races and ten of 11 state House races in Flathead County, according to preliminary results from Flathead County. Sen. Carl Glimm, R-Kila, was […]| Flathead Beacon
BILLINGS – Republican Tim Sheehy bolstered the GOP’s Senate majority with a victory over three-term Democratic U.S. Sen. Jon Tester in a contest of national importance that featured a record-setting torrent of spending by the two sides. Sheehy, a former U.S. Navy SEAL, closely aligned his campaign with Donald Trump and leading conservatives while painting […]| Flathead Beacon
WASHINGTON – Donald Trump was elected the 47th president of the United States on Wednesday, an extraordinary comeback for a former president who refused to accept defeat four years ago, sparked a violent insurrection at the U.S. Capitol, was convicted of felony charges and survived two assassination attempts. With a win in Wisconsin, Trump cleared the 270 […]| Flathead Beacon
This September, Istanbul’s only two Michelin-starred restaurant, TURK by Fatih Tutak, unveils its new addition: the AVLU Welcome Courtyard. This expansion introduces a dedicated space for socialising and relaxation, enhancing the venue’s already prestigious dining experience. Designed to reflect Turkey’s cultural heritage and natural beauty, AVLU promises to complement the restaurant’s modern yet timeless aesthetic. […]| The Upcoming
Mirazur, the multi-awarded restaurant located in Menton, has become the first of its kind worldwide to be awarded the B Corp certification, a label denoting high standards of social and environmental performance. Announced on September 6, 2024, this accolade follows a rigorous assessment process and highlights the establishment’s commitment to sustainability and ethical business practices. […]| The Upcoming
A 56-year-old Columbia Falls man was arrested early Wednesday morning following a standoff in which he allegedly shot at two separate people, law enforcement officers and a Two Bear Air helicopter. No one was injured in the incident and the suspect, Travis Myers, is in custody. Flathead County dispatch received a call at about 2 […]| Flathead Beacon
Inception Group will open a new bar, Cahoots: Postal Office, on 11th October in Borough Yards, near the iconic Borough Market in London. The venue is the latest addition to the Cahoots Network and is inspired by a 1940s post office. This new establishment will offer guests an immersive experience with interactive elements and inventive […]| The Upcoming
Hezbollah says this was phase one of a multi-part retaliation campaign for an assassinated of one of its commanders.| The War Zone
The Conro Trader was the last of three vessels that ferry large quantities of fuel across the Kerch Strait.| The War Zone
Anduril has laid out big plans for the Ghost Shark, one of which is now in the U.S., especially when it comes to proving out new payloads.| The War Zone
It still isn't perfectly clear what happened to the ship, but the explosion occurred at a key Russian port located in the Kerch Strait.| The War Zone
By pushing near the town of Tetkino, Ukraine could place an estimated 3,000 Russian troops in a pincer and clear several hundred more square kilometers of territory.| The War Zone
A converted commercial ship with an angled flight deck, the Shahid Bagheri looks strange but could fill a mission set that Iran has been developing for years. A converted commercial ship with an angled flight deck, the Shahid Bagheri looks strange but could fill a mission set that Iran has been developing for years.| The War Zone
From Moscow to Murmansk, Ukrainian drones have attacked targets across western Russia over the last 24 hours.| The War Zone
These are the only Secret Service vehicles that have been seen decked out for a candidate, with the Trump campaign doing the same in 2020.| The War Zone
Like the real thing, the virtual tank is operated by three individuals who used the custom-built simulator for war gaming.| The War Zone
The REFORPAC exercise will be a first-of-its-kind demonstration of how the Air Force expects to execute a high-end fight in the Pacific.| The War Zone
Spanish chef José Pizarro will be celebrating his 25th year in the UK with a special dining event on Saturday, 14th September at Pizarro Restaurant on Bermondsey Street, London. The event, organised in collaboration with Good Food, aims to highlight the signature dishes that have established Pizarro as a leading figure in Spanish cuisine in […]| The Upcoming
Influential studies from the VA St. Louis take a broad view of long Covid. Not every expert agrees with the approach.| Undark Magazine
After a nearly 21-year career with Montana Fish, Wildlife and Parks, the agency’s lead fisheries expert has resigned. Eileen Ryce, a fisheries biologist with a PhD, said inadequate support from her superiors while she ran a division that touches on two areas of critical interest in Montana — water and wildlife management — led her to […]| Flathead Beacon
The way we advertise products has changed drastically in the last decade. But what is it that makes an ad resonate with consumers and why?| SmartFrame
Scientists are debating whether microscopic blood clots are responsible for the wide range of symptoms in long Covid.| Undark Magazine
2023 brought tech many advancements but also ethical challenges like AI-weaponization & platform monopolies. But what stories stood out most?| SmartFrame