Targeted protein degradation (TPD) is a strategy used to selectively remove proteins from cells, rather than simply blocking their activity. Traditional small-molecule drugs work by binding to a protein and inhibiting its function, leaving the protein intact. In contrast, TPD harnesses the cell waste-disposal system—in particular, the ubiquitin-proteasome pathway—to tag the target protein for destruction. […] The post How Thalidomide and Molecular Glues Are Redefining Drug Discovery ap...| Promega Connections
In the late 1800s, quack medicine was rising concern in the United States. Harmful ingredients and ineffective medicines were a danger to the health of the country. This exhibit identifies the milestones in the federal government's efforts to regulate the drug market. … Continue reading The Great American Fraud: Quacks and quackery in medicine→| Melnick Medical Museum
This talk was given at the Annual Meeting of the International Society for Ethical Psychology and Psychiatry on October 28. The Video version of HealthCare Gone Mad is linked here. The slides and text are below. There will soon be an official ISEPP link to the talk and a Q and A, which will be| Dr. David Healy