Thousands of employees across HHS were terminated Monday evening after the U.S. Supreme Court ruled last week that the Trump administration could move forward with its sweeping reorganization of the agency.| BioSpace
While some analysts forecast the tariffs could mean billions in additional industry expenditure, others expect the overall impact to be “manageable.”| BioSpace
In an open letter addressing the Trump administration's proposed budget cuts to HHS, the executives urged Congress to continue “robust federal funding” for scientific research, which they say will help maintain U.S. biotech leadership globally.| BioSpace
Leerink Partners called the announcement a ‘positive’ given the delayed timeframe and the uncertainty that the administration will implement tariffs at all.| BioSpace
Roche’s reorganization of Spark Therapeutics is coming more into focus, with nearly 300 employees being let go by the end of this year. Spark also trimmed its staff in 2024.| BioSpace
President Trump also refused to promise pharma execs that he would hamstring the IRA’s drug negotiation program.| BioSpace
Roche is committing $50 billion while Regeneron inked a $3 billion manufacturing deal with Fujifilm, allowing the pharma to “nearly double” its U.S. large-scale manufacturing capacity.| BioSpace
Novartis plans to build seven new facilities in the U.S., touting the creation of up to 1,000 new jobs at the company. The new facilities will include a biomedical research hub in California, two radioligand plants, and four manufacturing sites.| BioSpace
The move comes after President Donald Trump warned Big Pharma leaders that he would impose tariffs on them if they refuse to reshore their manufacturing operations.| BioSpace
Johnson & Johnson follows Eli Lilly in spending billions on U.S. manufacturing after President Donald Trump threatened major tariffs on pharmaceutical products. Pfizer has also promised a similar commitment.| BioSpace
Despite a dip in sales and a recent schizophrenia stumble, the company drew an optimistic outlook for sales for the rest of the year, even as the specter of pharmaceutical tariffs looms.| BioSpace
Bristol Myers Squibb will make even deeper cuts to its organization to enhance efficiencies as it faces the 2028 loss of exclusivity for its blockbuster drugs Eliquis and Opdivo.| BioSpace
Bristol Myers Squibb announced Thursday it is implementing major cost-cutting measures including thinning out its management layers. The pharma also reported modest revenue growth despite taking a 6% sales hit for lung cancer therapy Opdivo.| BioSpace
Despite these cuts, the FDA should be able to stay above a "trigger" level that would prevent it from collecting fees from the pharma industry and deprive it of approximately half of its annual funding, according to The Washington Post.| BioSpace
continues from Chapter 9 - An event is just a fact, pure| Event Thinking
continues from Chapter 8 - The Death of the Aggregate| Event Thinking
continues from Chapter 7 - Focus on the behavior| Event Thinking
continues from Chapter 6 - The aggregate could cause unnecessary complexity| Event Thinking
continues from Chapter 5 - Event sourced aggregates are hard to refactor| Event Thinking
continues from Chapter 4 - The larger the Aggregate, the greater the contention| Event Thinking
continues from Chapter 3 - The aggregate mixes technical and business aspects| Event Thinking
continues from Chapter 2 - The Aggregate does not fit the story telling| Event Thinking
continues from Chapter 1 - I am here to kill the aggregate ...... One of the most powerful elements of DDD is that it has broken down the ...| sara.event-thinking.io
Massachusetts’ life sciences jobs grew by just 0.03% in 2024, according to a new MassBioEd report. Still, the report found encouraging signs for the industry, noting it’s expected to grow by 11.6% by 2029, adding an estimated 16,633 net new positions.| BioSpace
Explore the top 25 U.S. counties by estimated aggregate demand in 2024. Learn how construction trends, infrastructure investments, and population growth are driving demand for aggregates across key regions.| Mineralocity Aggregates
Bristol Myers Squibb has made significant cuts to its workforce since last year as part of a strategic reorganization aimed at saving $3.5 billion through 2027. The latest cuts in Lawrenceville, New Jersey, bring that area’s total number of disclosed cuts this year to 806.| BioSpace
As we continue to develop and refine the Mineralocity platform, we’re excited to share the powerful capabilities it offers for both greenfield exploration and high-level market research. Whether you’re looking to gain insight into a new area for mineral discovery or analyze broader market trends, Mineralocity is the tool to help you make data-driven decisions with ease.| Mineralocity Aggregates
Was asked recently about optimization of interesting case. There was table like: =$ CREATE TABLE input_data ( category_id INT8, object_id INT8, interaction_ts timestamptz, interaction_type TEXT, interaction_count INT4 ); And there was a code that was grouping it all by sum()ing interaction_count per category, object, interaction_type, and timestamp truncated to hour. Basically, storing somewhere result of: … Continue reading "Grouping data into array of sums – fun with custom aggregates"| select * from depesz;
As we move forward into another successful quarter, we want to take a moment to reflect on the value we’re committed to providing. At Burgex, we see our relationship with you as more than just service—it's about sharing knowledge, insights, and resources that empower your success.| Mineralocity Aggregates
2024 was a tough year for the biopharma industry, with several companies cutting hundreds or even thousands of employees. Follow along as BioSpace tracks job cuts and restructuring initiatives throughout 2025.| BioSpace
Here's a simple trick to get data.table aggregation to play nicely with multivariable functions.| Blair’s Science Desk