Why it matters: As human populations expand and environments shift, the human–animal interface grows—and with it, the risk of pathogens jumping species. Key finding: In an urban shelter cohort, Onchocerca lupi was detected in ~2% of dogs using a sensitive qPCR assay (1.9%), slightly higher than conventional PCR (1.6%). Takeaway: Monitoring shelter populations can surface low visibility threats and inform veterinary and public health response. The post What Shelter Dogs Can Tell Us About E...| Promega Connections
Metastasis of melanoma poses significant threats, especially to the brain, with low survival rates once advanced. A new microphysiological system developed by Reed-McBain et al. simulates tumor-stroma interactions in the brain, allowing for detailed metabolic assessments and visualization of nutrient diffusion. This innovative model offers potential improvements in therapeutic screening for melanoma brain metastases. The post Developing an Experimental Model System to Understand the Tumor Mic...| Promega Connections
Learn how a computation method can predict SARS-CoV-2 variants before they emerge and help us assess vaccine efficacy to prepare for a future pandemic.| Promega Connections
In the genomics era, the promise of precision medicine and tailored diagnostics is only as good as the datasets, which makes it imperative that those sets reflect the diversity of the human population. Populations from the African continent, the most genomically diverse region in the world, are underrepresented in current genomic data sets. Nowhere is […]| Promega Connections
Discover how far-red chemigenetic biosensors enable super-resolution, multiplexed imaging of kinase activity in live cells.| Promega Connections
Measles is associated with suppression of the immune system, which makes the host vulnerable to other infections even years after recovery.| Promega Connections
A new computational screening system using AI could lead to more efficient, cost-effective and expansive search for novel therapeutic drugs.| Promega Connections
