At Solve M.E., our mission is to drive research and advocacy efforts for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS), Long Covid, and other infection-associated chronic conditions and illnesses (IACCIs). This year, we have championed three critical appropriations requests to Congress, aiming to secure funding and resources to advance our cause. Two of our appropriations efforts are specific to ME/CFS. Below, we outline the purposes and significance of each of these efforts.