Table of Contents Spaced \(k\)-mers Minimap SPAdes MUMmer4 BLASR Bowtie 2 Patternhunter Spaced seeds improve \(k\)-mer-based metagenomic classification LoMeX Meeting notes Concepts: Mapping Map a sequence onto a reference genome/dataset Assembly Build a genome from a set of reads de novo (implied): without using a reference genome Otherwise just called mapping Typical complicating factors: read errors non-uniform coverage insert size variation chimeric reads (?) bireads non-uniform read cover...