Acknowledgement: A big thank you to Johanna Haffner of ETH Zürich for giving feedback on this! So I previously wrote Just know stuff. (Or, how to achieve success in a machine learning PhD.) Success in technical subjects requires, in large part, knowing a lot of stuff about that subject. Two years have gone by since then, and in the mean time the field of bioML has become this whole thing. Isomorphic are betting on structure prediction for small molecule therapeutics.