Saccharin, historical wrapping, Sugar Museum (Berlin) 1893 adSaccharin was produced first in 1879, by Constantin Fahlberg, a chemist working on coal tar derivatives in Ira Remsen's laboratory at Johns Hopkins University.[20] Fahlberg noticed a sweet taste on his hand one evening, and connected this with the compound benzoic sulfimide on which he had been working that day.[21][22] Fahlberg and Remsen published articles on benzoic sulfimide in 1879 and 1880.[10][23] In 1884, then working on hi...