First-Trimester Antibiotic Use for Urinary Tract Infection and Risk of Congenital Malformations The use of certain antibiotics to treat urinary tract infections (UTIs) during the first trimester of pregnancy may be associated with an increased risk of congenital malformations. In this cohort study of first-trimester antibiotic exposure, the risk of any malformation, severe cardiac malformation, […] The post Urgent Updates | July 17, 2025 first appeared on Urgent Care Association.