Dr. Polacheck’s laboratory investigates the physical interactions between cells and their environment and how forces at the cellular scale contribute to tissue development, homeostasis, and disease. To study how cells sense and generate forces in living tissue, the Polacheck lab develops microfluidic technology to build microtissues in the laboratory that mimic the architecture and multicellular function of human tissues in vivo. By integrating these organ-on-chip models with genome editing...