Fly! aims to make space missions accessible for all. For the first time, ESA is exploring whether an astronaut with a physical disability could embark on a long duration mission to the International Space Station. At the heart of the Fly! Project is John McFall, a former Paralympic athlete and orthopaedic surgeon who became a leg amputee after a motorcycle accident. The programme demonstrates ESA’s commitment to increasing diversity and expanding its pool of astronaut talent.