Background SMPDL3B (short for sphingomyelin phosphodiesterase acid-like 3B) is a protein that sits on the membrane of cells and influences lipids (fatty/waxy substances) within the membrane. Specifically, it tweaks levels of certain lipids called sphingolipids, which are both structural components of the cell membrane and signalling molecules. By regulating these lipids, SMPDL3B can affect how […]
