In this article, we explore the Frontier Nursing Service’s history from 1925 to 2025 through a chronological journey, highlighting the enduring themes that capture both the core mission that FNS stakeholders have consistently embraced, and the many ways that the service has changed. Indeed, whether we examine FNS leaders’ and staff members’ goals and accomplishments in the early years or recent years, we see throughlines of a focus on rural health, a dedication to primary care of the fa...