NIH supports the concept of Digital Twins as described in a 2024 report from the National Academies of Science, Engineering and Medicine (NASEM), as follows: "A Digital Twin is a set of virtual information constructs that mimics the structure, context, and behavior of a natural, engineered, or social system (or system-of-systems), is dynamically updated with data from its physical twin, has a predictive capability, and informs decisions that realize value. The bidirectional interaction betwee...