Patrick J. Loehrer, Sr., M.D., the Director of the Indiana University Melvin and Bren Simon Comprehensive Cancer Center, wrote a letter to all members of the Cancer Center this week about the use and abuse of science and scientists during the pandemic and throughout history. We’re publishing the letter as an IUCB blog, with Dr. Loehrer’s approval, since these topics are so central to thinking about ethics involving knowledge, uncertainty, and action during this pandemic.