Amiodarone prolongs the QT interval primarily by blocking potassium channels, delaying cardiac repolarization and extending the action potential duration. The Electrophysiological Basis of QT Interval Prolongation The QT interval on an electrocardiogram (ECG) represents the time from the start of ventricular depolarization to the end of ventricular repolarization. This interval reflects the total duration of […] The post How Does Amiodarone Prolong The QT Interval? | Cardiac Rhythm Secrets ...