This article (along with this article and many others) mentions some plots by CIA to overthrow the Cuban leader Fidel Castro: Staging the Second Coming so that the Cubans, still religious deep inside, would abandon their anti-clerical leader Poison him with thallium salts so that he would lose his beard, and with it, the political power, based in major part on his charismatic looks Giving him LSD before a live radio broadcast so that the incoherency of his speech would make people lose trust ...