To understand how prebunking can be best harnessed for Latino communities in the U.S., the Digital Democracy Institute of the Americas (DDIA) conducted the first-of-its kind randomized controlled trial (RCT) with U.S. Latino communities to test various approaches to inoculation against the manipulative techniques of emotional language, ad-hominem attacks, and false dichotomies. We offer fourteen best practices for tailoring prebunking and inoculation for Latino audiences in the U.S. in this l...