My recommendation for Mac power-user email client is MailMate. No question. No contest. However sometimes work security policies force you into Microsoft-Exchange-land and your only choice is to use Outlook for Mac You won’t ever be able to make Outlook work as well as MailMate, but you can do a few things to help you get closer. MailMate Smart Mailboxes can be somewhat mimicked using Outlook Smart Folder feature along with the Raw Query option.
