Thanks to AJ Kourabi for research assistance. Deep Brain Stimulators (source) Building on extant stereotactic neurosurgical tools and cardiac pacemaker technology, prototype DBS systems were first implanted in humans in the late 1960s. DBS performed in numerous patients until 1976, when the FDA was established. FDA stopped DBS sales until clinical trial data is submitted. No company was willing to run trials until the neurology field established clearer standards for patient improvement.