TurboGears, "the rapid web development megaframework you've been looking for", has just been released. It's the first web framework (for any language) that includes MochiKit in its war chest. TurboGears looks cool because it leverages a lot of very good existing software and wraps it up in a very usable manner. It does not have NIH syndrome. It has excellent documentation and a very nice 20 minute wiki tutorial that covers the whole stack (all the way up to "AJAX" with MochiKit!).