Bristol Myers Squibb is extending a research collaboration with the artificial intelligence company Insitro to design new medicines against a novel target in amyotrophic lateral sclerosis (ALS). The target was identified […] The post Insitro, Bristol Myers extend research into new drug for ALS appeared first on ALS News Today.| ALS News Today – The Web's Daily Resource for ALS News
People with amyotrophic lateral sclerosis (ALS) who also have diabetes tend to lose the ability to walk faster than non-diabetic patients, according to a study from Japan. The findings underscore […] The post Diabetes adds greater risk of mobility loss in ALS: Study appeared first on ALS News Today.| ALS News Today – The Web's Daily Resource for ALS News
EKZ-102, Eikonizo Therapeutics‘s experimental oral therapy for amyotrophic lateral sclerosis (ALS), is on track to enter early clinical testing in 2026, according to an announcement from the company. EKZ-102 is […] The post ALS therapy EKZ-102 on track to enter clinical testing in 2026 appeared first on ALS News Today.| ALS News Today – The Web's Daily Resource for ALS News
Last week, my husband, Todd, celebrated his 55th birthday — a milestone we never anticipated after he was diagnosed with ALS at age 39 in June 2010. For his 40th […] The post How life has changed since my husband’s first birthday with ALS appeared first on ALS News Today.| ALS News Today – The Web's Daily Resource for ALS News
Once in a while, there’s a topic on the ALS News Today Forums that inspires a new column. The question posted was a simple one: “Do you celebrate ALS-related anniversaries?” […] The post Now I celebrate the goals I meet, not the day of my ALS diagnosis appeared first on ALS News Today.| ALS News Today – The Web's Daily Resource for ALS News
Life Time will host a nationwide fitness event Oct. 25 to raise funds for ALS research and children’s health. The annual GO90: Move with Meaning challenge will take place at […] The post Life Time hosts nationwide fitness fundraiser for ALS research appeared first on ALS News Today.| ALS News Today – The Web's Daily Resource for ALS News
People with a history of traumatic brain injury (TBI) have a nearly three times higher risk of developing amyotrophic lateral sclerosis (ALS) than those who have not experienced a head […] The post Head trauma may be an early sign, not a cause of ALS: Study appeared first on ALS News Today.| ALS News Today – The Web's Daily Resource for ALS News
Using seven clinical measures that are fairly easy to assess, researchers have developed a machine learning model to help predict mortality in people with amyotrophic lateral sclerosis (ALS), according to […] The post AI model helps predict ALS mortality using clinical metrics appeared first on ALS News Today.| ALS News Today – The Web's Daily Resource for ALS News
“What do you think about having one thimbleberry design on one side of a mug and a different one on the other?” I asked my husband, Todd. We’d been brainstorming […] The post A project to work on together offers us a chance at getting unstuck appeared first on ALS News Today.| ALS News Today – The Web's Daily Resource for ALS News
A Phase 3 clinical trial testing pridopidine in people with ALS is expected to start enrolling patients in January.| ALS News Today
A conversation during a long walk with an old friend reminds columnist Kristin Neva that life is fragile and precious.| ALS News Today
When columnist Kristin Neva needs to be reminded to be kind to herself as an ALS caregiver, she remembers an old lesson from her younger self.| ALS News Today
Columnist Dagmar Munn is grateful for the talent that helps her find the humor in the varied struggles of her life with ALS.| ALS News Today
Columnist and caregiver Kristin Neva has found that living with ALS means that she lives with repeated stress over daily activities.| ALS News Today
Living with ALS means more than managing symptoms, says columnist Dagmar Munn, who also does breathing exercises to help strengthen her lungs.| ALS News Today
Columnist Kristin Neva and her husband, Todd, still find joy in cooking together creatively, especially during their meal prep.| ALS News Today
For columnist Juliet Taylor, fall brings back vivid memories of the October when her late husband, Jeff, was diagnosed with ALS.| ALS News Today
Ionis recently marked a decade of Surf Away+, a beach day of adaptive sports for people with neurological diseases, including ALS.| ALS News Today
Long-read DNA sequencing was found to be a more accurate method for detecting genetic defects linked to an increased risk of sporadic ALS.| ALS News Today
A year of treatment with AP-101 led to positive results for patients in a Phase 2 clinical trial, topline data showed.| ALS News Today
Through analyses of single strands of hair, researchers have shown that the dynamics of certain metal molecules are altered in ALS.| ALS News Today
Five students across Canada whose lives have been directly affected by ALS won scholarships for post-secondary education, ALS Canada said.| ALS News Today
When columnist Dagmar Munn's special footwear began to wear out, she went shoe shopping — which required a certain amount of resilience.| ALS News Today
Researchers genetically reprogrammed mouse nerve cells to reverse cell aging, delaying the onset of ALS symptoms in the animals.| ALS News Today
A repurposed veterinary medication, NUZ-001, helped ALS patients live longer and slowed disease progression in a long-term study.| ALS News Today
A brain-computer interface that can translate silent thoughts into spoken words may help speech-impaired people, including those with ALS.| ALS News Today
A new analysis found Radicava ORS (edaravone) slows functional decline and helps adults with amyotrophic lateral sclerosis (ALS) live longer.| ALS News Today
Due to a lack of resources and personnel, the FDA has delayed until October its decision on lifting a clinical hold on ALS drug NUZ-001.| ALS News Today
The ALS therapy ATH-1105 entered the brain and spinal cord at dose-proportional levels in healthy volunteers, and had a good safety profile.| ALS News Today
Coya Therapeutics got FDA clearance for a Phase 2 trial in the U.S. to investigate COYA 302 as an ALS treatment.| ALS News Today
Researchers have developed a blood-based test that shows high accuracy for diagnosing ALS as early as up to 10 years before symptom onset.| ALS News Today
This year's ALS Nexus conference allowed the community to connect with each other, celebrate recent advances, and share hope for the future.| ALS News Today
U.S. and China regulators have now cleared Sineugene Therapeutics' ALS gene therapy SNUG01 for clinical trials.| ALS News Today
Lila is a Science Writer at BioNews. She completed her PhD in neuroscience at the University of Washington, where she studied how the natural flexibility of the human brain can be used to promote recovery after injury. Previously, she has written about science for The Dallas Morning News and the...| ALS News Today
Patricia Inacio is a science writer for ALS News Today with a PhD in cell biology. She covers the latest news and information on a variety of amyotrophic lateral sclerosis topics.| ALS News Today
A trial that will test a noninvasive device called MyoRegulator as a treatment for ALS was cleared to start enrolling patients in the U.S.| ALS News Today
Columnist Dagmar Munn ponders the various things that people with ALS wait for, and shares a study with findings on what cultivates hope.| ALS News Today
Radicava (edaravone) is an approved infusion therapy used to slow functional decline in people with amyotrophic lateral sclerosis (ALS).| ALS News Today
Various adaptations and equipment are available that can help a person with ALS eat, dress, use the bathroom, and move around.| ALS News Today
The FDA has granted orphan drug status to Actimed Therapeutics' S-oxprenolol, a treatment candidate that aims to ease muscle wasting in ALS.| ALS News Today
Woolsey received three new U.S. patents covering innovations related to ROCK inhibitor Bravyl (oral fasudil), its investigational ALS drug.| ALS News Today
The analyses offer evidence for a slowing of functional decline and improved survival outcomes with long-term Radicava ORS by ALS patients.| ALS News Today
Neither memantine nor trazodone was able to slow amyotrophic lateral sclerosis (ALS) disease progression in a platform clinical trial.| ALS News Today
An analysis in 62 ALS patients who followed the Phase 2b study's rules (protocol) found a 37.4% ALSFRS-R difference with PrimeC vs. placebo.| ALS News Today
ALS speech problems are caused by a weakening of the muscles of the mouth and throat and worsen over time as the disease progresses.| ALS News Today
Mitochondrial genome mutations may be linked to ALS, per a study, opening the door for new ways of diagnosing and treating the disease.| ALS News Today
Certain rare genetic variants tied to Parkinson’s and other diseases raise the risk of developing ALS by more than three times, per a study.| ALS News Today
The first patient has been dosed in an open-label Phase 1/2 clinical trial of AMT-162, uniQure's one-time gene therapy for SOD1-ALS.| ALS News Today
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Exercise has multiple benefits for people with ALS, such as preserving muscle strength and mobility, and increasing overall quality of life.| ALS News Today
Columnist Dagmar Munn explains how she moved on from a mindset of "why bother?" after her ALS diagnosis. It helps her to live well.| ALS News Today
Two ALS centers launched an initiative to expand access to clinical trials and accelerate improvements in ALS research.| ALS News Today
After an ALS diagnosis, take time to decompress, learn about symptoms and treatment, look into voice banking, and make an advance care plan.| ALS News Today
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After columnist James Clingman's ALS diagnosis, he says he feared sleep. Now, it's a welcome escape to a world of late family and friends.| ALS News Today
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What columnist Dagmar Munn thought was an ALS symptom was just an impostor. "Learned nonuse" was her true problem, and she addressed it.| ALS News Today
An ALS diagnosis requires testing for signs of the neurodegenerative disease that rules out other disorders with similar symptoms.| ALS News Today
The scientists believe the algorithm they developed could be used to help patients and doctors make better treatment and care plans.| ALS News Today
Lindsey Shapiro is a science writer for ALS News Today with a PhD in neuroscience. She covers the latest news and information on a variety of amyotrophic lateral sclerosis topics.| ALS News Today
A gene therapy to increase nerve cell connectivity worked to ease motor dysfunction in an ALS mouse model but did not prolong survival.| ALS News Today
Esteban holds a Master of Science in Immunology from the Instituto Politécnico Nacional in Mexico, focused on inflammation and metabolism. With five years of experience as a Medical Science Liaison, he has worked directly with physicians across a wide range of specialties, covering topics...| ALS News Today
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ALS is a neurodegenerative condition that causes muscle weakness, movement problems, and breathing issues. Learn more about ALS symptoms here.| ALS News Today
Andrea Lobo holds a PhD in cell biology/neurosciences from the University of Coimbra-Portugal, where she studied stroke biology. As a research scientist for 19 years, Andrea participated in academic projects in multiple research fields, including stroke, gene regulation, cancer, and rare...| ALS News Today
About 90% of cases of amyotrophic lateral sclerosis (ALS) are characterized as sporadic ALS, meaning they occur spontaneously.| ALS News Today
The European Commission has approved Qalsody to treat ALS patients in the EU whose disease is associated with mutations in the SOD1 gene.| ALS News Today
The FDA granted conditional approval to tofersen, now Qalsody, for the treatment of ALS associated with mutations in the SOD1 gene.| ALS News Today
Qalsody (tofersen) is conditionally approved in the U.S. as treatment for amyotrophic lateral sclerosis associated with SOD1 gene mutations.| ALS News Today
When more than one person in the same biological family is affected by amyotrophic lateral sclerosis (ALS), it is known as familial ALS.| ALS News Today
Marisa Wexler is a senior science writer for ALS News Today with an MS in cellular and molecular pathology. She covers the latest news and information on a variety of amyotrophic lateral sclerosis topics.| ALS News Today
PrimeC slowed lung function decline and complication-free survival when treatment started early, per data from a Phase 2b ALS clinical trial.| ALS News Today
Starting treatment with PrimeC six months sooner was associated with slower disease progression and a survival benefit for ALS patients.| ALS News Today
The new intravenous formulation of ibudilast is expected to be useful for ALS patients who can't take medicine by mouth.| ALS News Today
ALS is a neurodegenerative condition that affects motor neurons. Learn about the causes and risk factors of ALS.| ALS News Today
Steve Bryson is a science writer for ALS News Today with a PhD in biochemistry. He covers the latest news and information on a variety of amyotrophic lateral sclerosis topics.| ALS News Today
Inspired by the Olympic athletes at the 2024 Paris Games, columnist Dagmar Munn shares the lessons she's applying to her life with ALS.| ALS News Today
Elevated blood and urine levels of metals like copper, selenium, and zinc raised disease risk by 3 times, and shortened patients' lives.| ALS News Today
ALS is a neurodegenerative disorder marked by progressively worsening muscle weakness and neurological dysfunction.| ALS News Today
Clene said it would submit additional CNM-Au8 clinical trial data and analysis to the FDA ahead of a planned meeting later this year.| ALS News Today
CNM-Au8 is an experimental liquid treatment for people with ALS that intends to increase cell energy.| ALS News Today
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Margarida Maia is a science writer for ALS News Today with a PhD in biomedical sciences. She covers the latest news and information on a variety of amyotrophic lateral sclerosis topics.| ALS News Today
There are several ALS treatment options that can help manage symptoms and slow the progression of the disease.| ALS News Today
A brain-computer interface allowed a man with amyotrophic lateral sclerosis to communicate through a computer that used his own voice.| ALS News Today
While traveling with friends, columnist Juliet Taylor is reminded of the importance of living out loud, especially in the face of ALS.| ALS News Today
A Penn State University researcher will use the $250,000 to identify and develop neuroprotective small molecules for ALS and like diseases.| ALS News Today
The selenium elevations with Qalsody may reflect a change in the antioxidant status of nerve cells, but more research is needed.| ALS News Today
Work using a new imaging technique found changes in how the SOD1 protein links with metal ions that seem key for how mutant SOD1 drives ALS.| ALS News Today
I AM ALS has launched the Cures Collective to collectively address unmeet needs in ALS and other neurodegenerative diseases.| ALS News Today
PrimeC led to improvements in iron accumulation in people with amyotrophic lateral sclerosis (ALS) in a clinical trial, new data showed.| ALS News Today
Clene submitted new data on CNM-Au8 to the FDA ahead of an upcoming meeting to discuss potential accelerated approval for the ALS therapy.| ALS News Today
The risk of death was nearly 60% lower in ALS patients given the experimental oral therapy CNM-Au8 than for an external placebo group, data show.| ALS News Today
ALS is a progressive neurological disorder that damages motor neurons. Learn more about types, causes, symptoms, diagnosis, and treatment.| ALS News Today