In a First, Brain-Wide Activity Mapped During Decision-Making
Two papers reveal insights into how decision-making unfolds across the entire brain in mice at single-cell resolution.| GEN - Genetic Engineering and Biotechnology News
A high-volume platform for rapidly constructing and characterizing antibodies, called oPool+ display, could potentially speed vaccine and therapeutic development. The post High-Throughput Antibody Platform May Transform Therapeutic Discovery appeared first on GEN - Genetic Engineering and Biotechnology News.| GEN – Genetic Engineering and Biotechnology News
By swapping key parts of the SCORE receptor, Riken scientists have demonstrated a mechanism for engineering plant immunity, paving the way for broad-spectrum pathogen resistance in economically important plants. The post Structural Swaps in SCORE Protein Enable Programmable Pathogen Recognition in Plants appeared first on GEN - Genetic Engineering and Biotechnology News.| GEN – Genetic Engineering and Biotechnology News
In mice, air pollution exposure triggered formation of an abnormal alpha-synuclein strain that shares key features with those of alpha-synuclein found in the brains of patients with Lewy body dementia. The post Possible Molecular Link Between Air Pollution and Lewy Body Dementia Identified appeared first on GEN - Genetic Engineering and Biotechnology News.| GEN – Genetic Engineering and Biotechnology News
In this GEN webinar, our expert speakers—Tom Brennan (VP Nuclear Medicine at Marken-UPS Healthcare Precision Logistics) and John Zehner (CEO/President of SpectronRx)—will describe the extraordinary journey of a radiopharmaceutical dose and explore the sophisticated dance of just-in-time manufacturing, real-time GPS and temperature tracking, and the intricate coordination required between production facilities, specialized couriers, and clinical teams. The post Radiopharmaceutical Pathways...| GEN – Genetic Engineering and Biotechnology News
TTX-381, a one-time, subretinal AAV gene therapy, is designed to deliver a functional TPP1 gene copy directly to retinal cells to produce the missing TPP1 enzyme and preserve patient vision. The post Andelyn and Tern Therapeutics Partner on Gene Therapy Manufacturing appeared first on GEN - Genetic Engineering and Biotechnology News.| GEN – Genetic Engineering and Biotechnology News
Women of reproductive age seem to be less susceptible to CKD than men, but the molecular mechanisms were not well understood. Paola Romagnani, MD, PhD, speaks with GEN about the estrogen-driven protective effect against CDK. The post Estrogen Signaling Impacts Kidney Cell Regeneration with Links to Preeclampsia appeared first on GEN - Genetic Engineering and Biotechnology News.| GEN – Genetic Engineering and Biotechnology News
In this webinar, The post How Bioprocessing Breakthroughs Are Shaping the Future of Medicine appeared first on GEN - Genetic Engineering and Biotechnology News.| GEN – Genetic Engineering and Biotechnology News
Preclinical studies showed how anemia in bone metastasis occurs when the cancer cells commandeer specialized macrophages that normally recycle iron in the bone, depriving the red blood cells of necessary iron, and helping the tumor to continue to grow. The post Anemia in Bone Metastasis Results When Cancer Cells Hijack Iron-Recycling Macrophages appeared first on GEN - Genetic Engineering and Biotechnology News.| GEN – Genetic Engineering and Biotechnology News
Early-stage findings suggest that blocking the ABHD18 gene may restore mitochondrial function and improve heart function in Barth syndrome, a rare, often fatal genetic disorder that lacks effective therapies. The post Preclinical Data Spotlights Gene with Therapeutic Potential for Barth Syndrome appeared first on GEN - Genetic Engineering and Biotechnology News.| GEN – Genetic Engineering and Biotechnology News
Two papers reveal insights into how decision-making unfolds across the entire brain in mice at single-cell resolution.| GEN - Genetic Engineering and Biotechnology News
Antibodies from a person who had previously been infected with mpox provides full protection from severe illness and death in mice.| GEN - Genetic Engineering and Biotechnology News
Thermo Fisher has more than doubled in size in the U.S. since 2017, now employing more than 50,000 people in the country today.| GEN - Genetic Engineering and Biotechnology News
In GEN’s flagship virtual event, The State of Biotech, outstanding research and business leaders from industry and academia will discuss the latest research developments, innovations, new technologies, and convulsive regulatory changes that are reshaping the world of biotech.| GEN - Genetic Engineering and Biotechnology News
The invention of CRISPR and DNA sequencing has provided the necessary tools for rapidly engineering CHO cells along with a parts list.| GEN - Genetic Engineering and Biotechnology News
The movement of epithelial cells during wound healing is mediated by the endoplasmic reticulum, which senses the curvature of wound gaps.| GEN - Genetic Engineering and Biotechnology News
Researchers suggest targeting inflammation may offer a promising therapeutic strategy at the intersection of cancer and cardiovascular disease.| GEN - Genetic Engineering and Biotechnology News
VantAI's AI platform will accelerate programmable protein interaction therapies across Halda's cancer and immunology indications.| GEN - Genetic Engineering and Biotechnology News
Researchers demonstrate that an engineered antibody improves a class of drugs that has struggled to make good on its early promise.| GEN - Genetic Engineering and Biotechnology News
Get the latest news and information on genetic engineering and biotechnology including analysis, features, webinars, podcasts, and more.| GEN - Genetic Engineering and Biotechnology News
Landmark single-cell dataset of one billion cells will be used to train new AI models to advance understanding of cellular behavior and gene function.| GEN - Genetic Engineering and Biotechnology News
Trained on data covering 1.5 billion years of evolution, CZI’s new generative AI model probes cellular biology across species for therapeutic applications.| GEN - Genetic Engineering and Biotechnology News
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GREmLN leverages a graph-based architecture to represent gene-gene interactions to predict cell behavior for therapeutic applications.| GEN - Genetic Engineering and Biotechnology News
Agilis Biotherapeutics has been awarded a Cooperative Research and Development Agreement by National Center for Accelerating Translational Sciences (NCATS) to facilitate development of the company’s gene-therapy candidate for aromatic L-amino acid decarboxylase (AADC) deficiency.| Powell Gene Therapy Center » College of Medicine » University of ...
Eight babies, born following Mitochondrial Donation treatment to reduce transmission of mitochondrial DNA disease, show no signs of illness.| GEN - Genetic Engineering and Biotechnology News
Massively Parallel Ribosome Profiling (MPRP) enables rapid identification of viral proteins without the need to grow live viruses.| GEN - Genetic Engineering and Biotechnology News
Scientists believe the lymphoid organ-chip should be an asset in the face of a rapidly evolving SARS-CoV-2 pandemic.| GEN - Genetic Engineering and Biotechnology News
