Simtra BioPharma Solutions advances sterile injectable manufacturing through major expansions in the U.S. and Germany, leveraging strategic partnerships and technical innovation to accelerate complex biologics, including ADCs and GLP-1 therapies, for global pharmaceutical clients. The post Simtra BioPharma Expands Global Footprint appeared first on GEN - Genetic Engineering and Biotechnology News.| GEN – Genetic Engineering and Biotechnology News
An academia-industry collaboration has developed a new sampling algorithm for Design of Experiment (DoE), which can explain its trade-offs between multiple variables. They hope it will democratize experimental design beyond specialist data scientists. The post Researchers Develop Intelligent Model for Aiding Design of Experiment appeared first on GEN - Genetic Engineering and Biotechnology News.| GEN – Genetic Engineering and Biotechnology News
Reducing the number of manual steps involved in cell therapy production using automation would help the industry reduce staffing costs, improve consistency, and help more patients gain access to these potentially lifesaving medicines, say researchers. The post Reduce Staffing Costs and Boost Access with Cell Therapy Automation appeared first on GEN - Genetic Engineering and Biotechnology News.| GEN – Genetic Engineering and Biotechnology News
This new, functionalized 3D chimeric protein scaffold recapitulates the physiological interactions of pluripotent stem cells with surrounding extracellular matrix, thus better mimicking human tissue. It offers up to 25-fold hiPSC proliferation. The post Functionalized Fibrin Gel Spurs In-Gel Production of hiPSCs appeared first on GEN - Genetic Engineering and Biotechnology News.| GEN – Genetic Engineering and Biotechnology News
In this GEN webinar, Nik Ekman will discuss critical considerations for scaling cell therapy processes from research through commercialization. The post Scaling Cell Therapy Development from Research to Commercialization appeared first on GEN - Genetic Engineering and Biotechnology News.| GEN – Genetic Engineering and Biotechnology News
Recursion, Roche, and its Genentech subsidiary have unveiled the latest product of their nearly four-year artificial intelligence (AI) drug discovery collaboration, a whole-genome map of specialized microglial immune cells that the companies plan to use toward revealing significant new targets in neurodegenerative diseases. The post Recursion, Roche Unveil Microglia Map of Neuro Disease Targets appeared first on GEN - Genetic Engineering and Biotechnology News.| GEN – Genetic Engineering and Biotechnology News
A computational method was developed to create synthetic receptors called T-SenSERs that are engineered to detect soluble signals found in tumors and convert them into co-stimulatory or cytokine-like signals that boost anticancer T cell activity. The post Computationally Designed Receptors Help Engineered T Cells Control Tumors appeared first on GEN - Genetic Engineering and Biotechnology News.| GEN – Genetic Engineering and Biotechnology News
By sustaining higher viable cell densities, extending culture duration, and enabling continuous product harvest, perfusion cell culture allows manufacturers to increase volumetric productivity while reducing cost of goods. The post Scaling Perfusion: How Small-Scale ATF Systems Bridge the Gap to Commercial mAb Manufacturing appeared first on GEN - Genetic Engineering and Biotechnology News.| GEN – Genetic Engineering and Biotechnology News
In this GEN webinar, LV expert Brianna Jayanthi, PhD, will discuss how Asimov's LV Edge Producer and Packaging Systems are leading to higher-quality, higher-productivity cell lines to support clinical and commercial LV therapies. The post Next-Gen Lentiviral Vector Manufacturing: Improving Scalability, Control, and Quality appeared first on GEN - Genetic Engineering and Biotechnology News.| GEN – Genetic Engineering and Biotechnology News
Electra Therapeutics has completed an oversubscribed $183 million Series C financing it said will fund a global pivotal trial of its lead pipeline candidate, a frontline treatment for secondary hemophagocytic lymphohistiocytosis (sHLH).| GEN - Genetic Engineering and Biotechnology News
Researchers in China have determined to identify the genetic basis for the naked mole-rats’ increased longevity.| GEN - Genetic Engineering and Biotechnology News
Connecting clinical centers to industrial-grade autologous therapy manufacturing enhances therapeutics and processing efficiency.| GEN - Genetic Engineering and Biotechnology News
Results reported in a preprint connect localized signals in the brain to aging-related changes in immune cells in mouse models.| GEN - Genetic Engineering and Biotechnology News
Two papers reveal insights into how decision-making unfolds across the entire brain in mice at single-cell resolution.| GEN - Genetic Engineering and Biotechnology News
Antibodies from a person who had previously been infected with mpox provides full protection from severe illness and death in mice.| GEN - Genetic Engineering and Biotechnology News
The invention of CRISPR and DNA sequencing has provided the necessary tools for rapidly engineering CHO cells along with a parts list.| GEN - Genetic Engineering and Biotechnology News
The movement of epithelial cells during wound healing is mediated by the endoplasmic reticulum, which senses the curvature of wound gaps.| GEN - Genetic Engineering and Biotechnology News
Researchers suggest targeting inflammation may offer a promising therapeutic strategy at the intersection of cancer and cardiovascular disease.| GEN - Genetic Engineering and Biotechnology News
VantAI's AI platform will accelerate programmable protein interaction therapies across Halda's cancer and immunology indications.| GEN - Genetic Engineering and Biotechnology News
Researchers demonstrate that an engineered antibody improves a class of drugs that has struggled to make good on its early promise.| GEN - Genetic Engineering and Biotechnology News
Landmark single-cell dataset of one billion cells will be used to train new AI models to advance understanding of cellular behavior and gene function.| GEN - Genetic Engineering and Biotechnology News
Trained on data covering 1.5 billion years of evolution, CZI’s new generative AI model probes cellular biology across species for therapeutic applications.| GEN - Genetic Engineering and Biotechnology News
Copyright © 2025 Sage Publications or its affiliates, licensors, or contributors. All rights reserved, including those for text and data mining and training of large language models, artificial intelligence technologies, or similar technologies.| GEN - Genetic Engineering and Biotechnology News
GREmLN leverages a graph-based architecture to represent gene-gene interactions to predict cell behavior for therapeutic applications.| GEN - Genetic Engineering and Biotechnology News
Agilis Biotherapeutics has been awarded a Cooperative Research and Development Agreement by National Center for Accelerating Translational Sciences (NCATS) to facilitate development of the company’s gene-therapy candidate for aromatic L-amino acid decarboxylase (AADC) deficiency.| Powell Gene Therapy Center » College of Medicine » University of ...
