BMC Psychiatry is an open access, peer-reviewed journal that encompasses a wide range of topics related to psychiatric disorders. Welcomes both basic and ...| BioMed Central
Background The evidence on selective serotonin reuptake inhibitors (SSRIs) for major depressive disorder is unclear. Methods Our objective was to conduct a systematic review assessing the effects of SSRIs versus placebo, ‘active’ placebo, or no intervention in adult participants with major depressive disorder. We searched for eligible randomised clinical trials in The Cochrane Library’s CENTRAL, PubMed, EMBASE, PsycLIT, PsycINFO, Science Citation Index Expanded, clinical trial registers...| BioMed Central
Background Psychological problems such as depression and anxiety increase the risk of cognitive impairment in older adults. But mechanisms on the effect of psychological disorder on cognitive function is inconclusive. Repetitive negative thinking (RNT) is a core symptom of a number of common psychological disorders and may be a modifiable process shared by many psychological risk factors that contribute to the development of cognitive impairment. RNT may increase the risk of cognitive impairm...| BioMed Central
Background There are many articles reporting that the component of intestinal microbiota implies a link to anxiety disorders (AD), and the brain-gut axis is also a hot topic in current research. However, the specific relevance between gut microbiota and AD is uncertain. We aimed to investigate causal relationship between gut microbiota and AD by using bidirectional Mendelian randomization (MR). Methods Genetic instrumental variable (IV) for the gut microbiota were obtained from a genome-wide ...| BioMed Central
Attention-deficit/hyperactivity disorder (ADHD) in the adult population is frequently associated with comorbid psychiatric diseases that complicate its recognition, diagnosis and management.The prevalence of ADHD in the general adult population is 2.5% and it is associated with substantial personal and individual burden. The most frequent comorbid psychopathologies include mood and anxiety disorders, substance use disorders, and personality disorders. There are strong familial links and neuro...| BioMed Central
Background Telemedicine is a strategy for overcoming barriers to access evidence-based psychotherapy. Digital modalities that operate outside session-based treatment formats, such as ongoing two-way messaging, may further address these challenges. However, no study to date has established suitability criteria for this medium. Methods A large outpatient sample (n = 10,718) engaged in daily messaging with licensed clinicians from a telemedicine provider. Patients consisted of individuals fr...| BioMed Central