Dr. Purdue is an internationally recognized expert in the study of cancer associations with occupational and environmental exposures to chlorinated solvents, per- and polyfluoroalkyl substances (PFAS) and other agents, and the etiology of kidney cancer.| dceg.cancer.gov
DCEG is a world leader in cancer epidemiology and genetics research, dedicated to training the next generation of scientists.| dceg.cancer.gov
The ESCUDDO Efficacy Trial is a scientific evaluation of one or two doses of the human papillomavirus (HPV) bivalent or nonavalent prophylactic vaccines| dceg.cancer.gov
The BEEA study, a subcohort for molecular epidemiologic investigations within the Agricultural Health Study, was conducted to better understand the biological mechanisms through which pesticides and other agricultural exposures may influence risk of various cancers.| dceg.cancer.gov
A listing of principal investigators in the Occupational and Environmental Epidemiology Branch (OEEB). Learn about their research interests.| dceg.cancer.gov
Dr. Mark Purdue applies molecular and classical epidemiologic methods to study the causes of cancer and improve exposure assessment. He is particularly interested in evaluating the potential carcinogenicity of per- and polyfluoroalkyl substances and chlorinated solvents, and investigating the etiology of kidney cancer.| dceg.cancer.gov
Using data from the Multiethnic Cohort Study, Jongeun Rhee, Vicky Chang, Mark Purdue, and Jonathan Hofmann in the Occupational and Environmental Epidemiology Branch led the first study to explore the relationship between PFAS and kidney cancer in different racial and ethnic groups.| dceg.cancer.gov
Jonathan Hofmann and collaborators find that perfluorooctanoic acid (PFOA) is associated with increased risk of kidney cancer in cohort with PFAS concentrations comparable to those found in the general population.| dceg.cancer.gov
Dr. Jonathan Hofmann focuses his research on understanding the carcinogenic potential of pesticides and other agricultural exposures and PFAS. He also uses molecular epidemiologic approaches to investigate the etiology and natural history of multiple myeloma and its precursor monoclonal gammopathy of undetermined significance (MGUS).| dceg.cancer.gov
Dr. Mark Purdue and colleagues found that higher levels of PFOS, a specific PFAS, in blood collected from U.S. Air Force servicemen was associated with higher risk of developing testicular cancer.| dceg.cancer.gov
DCEG investigators have developed a portfolio of research aimed at identifying cancer-types associated with per- and polyfluoroalkyl substances (PFAS). These studies are innovative for their direct assessment of exposure using banked serum specimens as well as their evaluation of risks at varying exposure levels, from occupational exposure to those found in the general population or among military personnel.| dceg.cancer.gov