A study using massive biobank databases has revealed associations between gastrointestinal tract disorders and the neurodegenerative diseases Alzheimer’s and Parkinson’s, and has characterized their genetic and proteomic links. The post Gut Disorders Linked with Alzheimer’s and Parkinson’s Neurodegeneration appeared first on Inside Precision Medicine.| Inside Precision Medicine
Transdermal estradiol, (E2) given with either patches or gels, was associated with better memory of words or events, while oral administration of estradiol was linked with improved prospective memory, or remembering to do things in the future. The post Estradiol Delivery Method Tied to Memory Differences After Menopause appeared first on Inside Precision Medicine.| Inside Precision Medicine
A biomarker present in 20% of ER+/HER2− breast cancers has been identified, with potential to predict heightened sensitivity to CDK4/6 inhibitor drugs. The post Biomarker Discovery Could Improve Personalized Care in ER+ Breast Cancer appeared first on Inside Precision Medicine.| Inside Precision Medicine
A first-in-human trial testing a novel allogeneic synthetic TCR and antigen receptor (STAR) T cell therapy has shown encouraging early results in patients with severe, treatment-resistant systemic lupus erythematosus (SLE). The post STAR T, An Allogeneic CAR T Alternative, Is Effective in Lupus Patients appeared first on Inside Precision Medicine.| Inside Precision Medicine
Measuring acoustic emissions from microbubbles during focused ultrasound may help researchers standardize blood-brain barrier opening during glioma treatment. The post Glioma Treatment May Benefit from Acoustic Biomarker–Guided BBB Opening appeared first on Inside Precision Medicine.| Inside Precision Medicine
Tamoxifen fuels uterine cancer by activating the PI3K pathway, according to a new study, bypassing mutations normally required. Findings point to potential strategies to reduce risk while preserving the drug’s breast cancer benefits. The post How Tamoxifen Raises Uterine Cancer Risk—and a Path to Prevention appeared first on Inside Precision Medicine.| Inside Precision Medicine
Triple-negative breast cancer in this population was largely similar to that of Asian American and non-Hispanic white women. The post Triple-Negative Breast Cancer Mutations Mapped in Black Women appeared first on Inside Precision Medicine.| Inside Precision Medicine
The research used CRISPR/Cas9 to develop an in vivo screen of MYC-driven lymphoma in mouse models to show that the loss of NPRL3, DEPDC5, or NPRL2 in the GATOR1 complex significantly accelerates lymphoma development. The post CRISPR Screen Identifies GATOR1 as Lymphoma Tumor Suppressor appeared first on Inside Precision Medicine.| Inside Precision Medicine
Implanting donor heart valves in children with congenital heart disease can be safe and effective and reduces the number of operations children need as they grow, research shows. The post Transplanting Heart Valves Effective Option for Congenital Heart Disease appeared first on Inside Precision Medicine.| Inside Precision Medicine
PGT-A for women 35 to 42, a group that has a higher risk of producing embryos with chromosomal abnormalities, could improve IVF success.| Inside Precision Medicine
Andrea Califano, PhD, Chan Zuckerberg Biohub New York’s founding director, explains the AI model for predicting how gene networks drive cell behavior.| Inside Precision Medicine
Teal Health has announced the launch of their Teal Wand at-home cervical cancer screening kit and virtual telehealth services in California.| Inside Precision Medicine
The device detects infection via temperature, pH, and inflammation markers such as C-reactive protein (CRP) and interleukin-6 (IL-6).| Inside Precision Medicine
DunedinPACNI quantifies the rate of biological aging in midlife to forecast risks for dementia, chronic disease, and death in older adulthood.| Inside Precision Medicine
Glipizide, a widely prescribed drug for type II diabetes, can increase the five-year risk of major cardiovascular events by 13%.| Inside Precision Medicine
A team of researchers using single-cell sequencing has uncovered how cancer cells prevent cells in their environment from fighting the tumor.| Inside Precision Medicine
New research shows how glioblastoma cells infiltrate the brain and which key genes drive the invasion, paving the way to new treatments.| Inside Precision Medicine
A new mRNA cancer vaccine, in combination with common immunotherapy drugs, could become the first universal cancer vaccine.| Inside Precision Medicine
AI model outperforms cardiologists in detecting hidden structural heart disease from routine ECGs, advancing early screening.| Inside Precision Medicine
The allogeneic Azer-cel showed impressive response rates in a Phase Ib study with DLBCL patients who had failed autologous CAR T cell therapy treatments.| Inside Precision Medicine
Cancer deaths linked to obesity have tripled in the U.S. over the past two decades, according to a study presented Sunday at ENDO.| Inside Precision Medicine
Mapping blood stem cell metabolism reveals choline as a key nutrient to preserve stem cell health and guide precision therapies.| Inside Precision Medicine
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Long-term obesity may trigger aging molecular signals in young adults including epigenetic modifications and telomere shortening, researchers have discovered.| Inside Precision Medicine
Inside Precision Medicine is the only global media brand covering the full spectrum of precision medicine, taking a wide lens approach while bringing into sharp focus the many complex and interconnected issues that constitute the field.| Inside Precision Medicine
Without reference to the regulatory and reimbursement structures that govern the translation of science and technology into practice and without a concerted effort by both providers and payers to integrate innovative new discoveries in science and technology into clinical care, patients will have to wait longer for medicine to truly become personalized, predictive, and preventive.| Inside Precision Medicine