This set of Institutional Best Laboratory Practices is designed for the authentication of cell lines and tissue samples used in biomedical research. The document sets out four best practices, which include: The Institutional Best Laboratory Practices include detailed recommendations for how these four best practices can be implemented in research laboratories. The document replaces a […]| ICLAC
This document was written to set out the essential steps for authenticating human cell lines. The Guide focuses on short tandem repeat (STR) profiling, as a widely used and accepted authentication method. The Guide includes sections on: You might like to read more about authenticating cell lines. See our reference pages for authenticating human cell lines and non-human cell […]| ICLAC
This document was written to set out the essential steps for authenticating mouse cell lines. The Guide focuses on short tandem repeat (STR) profiling, as a widely used and accepted authentication method. The Guide includes sections on: You might like to read more about authenticating cell lines. See our reference pages for authenticating human cell lines and non-human cell […]| ICLAC
This checklist was written as a resource for scientists who are preparing to write or review manuscripts and grant applications. The list can be used to help determine if the cell lines used for the work meet acceptable quality requirements.| ICLAC
Advice to Scientists: Making Cell Line Authentication Part of Everyday Culture Practice| ICLAC
This document was written to help scientists find unique names for newly established cell lines. ICLAC has noticed an increasing number of cell lines with identical names but coming from different donors. To help address the problem, this document sets out: Numerical identifiers are also important to identify and track cell lines in publications. For more information […]| ICLAC
The seminar slides are designed as a short, engaging presentation about cell line authentication. Topics include why authentication is important, the impact of misidentified cell lines, and a brief description of STR profiling. At the end of the slide deck is a figure showing the various cell line problems that occur with time in culture, […]| ICLAC
The training module is designed to explore various aspects of cell line authentication. Three separate slide decks are included, courtesy of Bio-Trac and in memory of Roland Nardone. Human Cell Line Authentication Discusses why authentication is necessary, when to test, and what methods are available with a focus on STR genotyping. The Basics of STR […]| ICLAC
Watch The Hidden World of Cell Lines on YouTube Visit the companion page for scientific background and information The Hidden World of Cell Lines video is a short, engaging introduction to cell lines and their problems. It is designed for anyone who is new to cell culture or cell lines, with no prior understanding required. […]| ICLAC
Version 11 of the ICLAC Register of Misidentified Cell Lines was released on 8 June 2021.| ICLAC
