Study Sheds Light on Frequency, Treatment of Common Liver Cancer in Younger Patients
Defining early-onset HCC| Cancer Center at Illinois
Defining early-onset HCC| Cancer Center at Illinois
2020 Recipients| Cancer Center at Illinois
Essential to Chen’s study is a foundational understanding of the tumor microenvironment (TME) and tumor-associated macrophages (TAMs). The TME, comprising various immune cells, plays a crucial role in shaping an immunosuppressive landscape that promotes tumor development, progression, metastasis, and resistance to therapy. Among the immune cells in the TME, TAMs are the most abundant and are known to exert potent immunosuppressive functions, supporting tumor growth, and immune evasion.| Cancer Center at Illinois
Initial seed funding from the CCIL was later boosted by grants from the National Cancer Institute, Prostate Cancer Foundation, and the Department of Defense. The team also collaborated with Karen Sfanos at Johns Hopkins University, a pioneer in studying the link between the microbiome and prostate cancer.| Cancer Center at Illinois
