Tiny vesicles may reduce vascular remodeling in PH: Rat study
Exosomes released by mesenchymal stem cells may help reduce vascular remodeling and ease PH symptoms, a rat study showed.| Pulmonary Hypertension News
Learn more about pulmonary hypoxic hypertension, which is caused by a shortage of oxygen in the body (hypoxia), and classified as a type of group 3 pulmonary hypertension by the World Health Organization (WHO).| Pulmonary Hypertension News
Exosomes released by mesenchymal stem cells may help reduce vascular remodeling and ease PH symptoms, a rat study showed.| Pulmonary Hypertension News
LungFit PH, Beyond Air's nitric oxide therapy device, has received the European CE mark approval for pulmonary hypertension in newborns.| Pulmonary Hypertension News
Steve Bryson is a science writer for Pulmonary Hypertension News with a PhD in biochemistry. He covers the latest news and information on a variety of pulmonary hypertension topics.| Pulmonary Hypertension News
Read about the different classes of the World Health Organization's (WHO) Pulmonary Hypertension Functional Classification.| Pulmonary Hypertension News
Three months of CS1 therapy boosted quality of life, while symptoms tied to heart failure and clinical worsening and mortality risk declined.| Pulmonary Hypertension News
The U.S. FDA has granted orphan drug designation to CS1, Cereno Scientific’s lead therapy candidate for treating pulmonary arterial hypertension (PAH).| Pulmonary Hypertension News
Cereno's expanded access program for investigational therapy CS1 covers 10 PAH patients, following a Phase 2a clinical trial.| Pulmonary Hypertension News
The investigational therapy CS1 led to beneficial changes in for people with pulmonary arterial hypertension in a Phase 2a clinical trial.| Pulmonary Hypertension News
The FDA has approved the use of Cereno Scientific’s CS1 in an extension of the ongoing Phase 2 trial testing the therapy in people with PAH.| Pulmonary Hypertension News
Read about his other PH news from around the web.| Pulmonary Hypertension News
Treatment with a combination of sildenafil and statins improved exercise capacity and reduced pulmonary arterial pressure in people with pulmonary hypertension (PH) secondary to chronic obstructive pulmonary disease (COPD) — a condition known for short as COPD-PH — according to a review study by scientists in China. These findings, culled from a dozen trials conducted […] The post Sildenafil-statin combo found to boost exercise capacity in COPD-PH appeared first on Pulmonary Hypertensio...| Pulmonary Hypertension News – The Web's Daily Resource for PH News
Yutrepia (inhaled treprostinil), an inhaled dry powder formulation of treprostinil for pulmonary arterial hypertension (PAH) and pulmonary hypertension (PH) associated with interstitial lung disease (PH-ILD), has been prescribed to more than 900 people with PAH and PH-ILD since its approval in the U.S. in May, according to its developer Liquidia. Overall, more than 550 patients […] The post Yutrepia beefs up exercise capacity in adults with PH-ILD in trial appeared first on Pulmonary Hypert...| Pulmonary Hypertension News – The Web's Daily Resource for PH News
Those of us in rare disease communities have learned one lesson particularly well: We all must listen to our bodies. That’s why a celebration like National Relaxation Day — which happens to be Aug. 15, the day this column was published — is such an apt reminder. Many will take this opportunity to relax and […] The post Why a day of rest is a victory with pulmonary hypertension appeared first on Pulmonary Hypertension News.| Pulmonary Hypertension News – The Web's Daily Resource for PH News
A study found that changes in immune cell metabolism may underlie increases in inflammatory signaling molecules in people with pulmonary arterial hypertension (PAH), suggesting that targeting immune cell metabolism could be a treatment strategy for the condition. The study, “Metabolic changes of peripheral blood mononuclear cells are related to the high cytokine levels in patients […] The post Immune cell metabolism may point to PAH treatment strategy appeared first on Pulmonary Hypertens...| Pulmonary Hypertension News – The Web's Daily Resource for PH News
Tectonic Therapeutic plans to launch a Phase 2 clinical trial to test the impact of its therapy candidate TX45 on blood flow, or hemodynamics, in people with pulmonary hypertension and interstitial lung disease (PH-ILD). The move comes on the heels of positive results from part A of a Phase 1b clinical trial, which showed that […] The post Tectonic planning trial to test TX45 impact on blood flow in PH-ILD appeared first on Pulmonary Hypertension News.| Pulmonary Hypertension News – The Web's Daily Resource for PH News
People with portopulmonary hypertension (PoPH), a form of pulmonary arterial hypertension (PAH) usually associated with liver disease, show lower five-year survival rates than people with other types of PAH. Common markers that help predict outcomes in other PAH forms failed to identify high-risk patients in this group, however. But PAH-targeted therapies were linked to improved […] The post PAH therapies extend survival in portopulmonary hypertension appeared first on Pulmonary Hypertensio...| Pulmonary Hypertension News – The Web's Daily Resource for PH News
“Why am I so tired all the time?” If you’ve ever thought that while managing your pulmonary hypertension (PH), you’re not alone. Fatigue is a well-known PH symptom that often goes unaddressed. In my experience, sleep plays a factor in my fatigue levels. Despite getting what I thought was enough sleep, I’d often wake up […] The post Practical strategies can help reduce fatigue while living with PH appeared first on Pulmonary Hypertension News.| Pulmonary Hypertension News – The Web's Daily Resource for PH News
A 5-year-old boy with a neuroblastoma developed PAH after receiving a high dose of chemotherapy to prepare for a stem cell transplant.| Pulmonary Hypertension News
Marisa Wexler is a senior science writer for Pulmonary Hypertension News with an MS in cellular and molecular pathology. She covers the latest news and information on a variety of pulmonary hypertension topics.| Pulmonary Hypertension News
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Corvista Health’s point-of-care device, used to predict pulmonary hypertension (PH), also appears to work well at identifying heart failure.| Pulmonary Hypertension News
The FDA granted breakthrough device designation to CorVista for its system diagnosing pulmonary hypertension and cardiovascular disorders.| Pulmonary Hypertension News
Margarida Maia is a science writer for Pulmonary Hypertension News with a PhD in biomedical sciences. She covers the latest news and information on a variety of pulmonary hypertension topics.| Pulmonary Hypertension News
The Aeson Total Artificial Heart helped three people with heart failure and pulmonary hypertension become eligible for a heart transplant.| Pulmonary Hypertension News
The immune protein STAT6 may be a driver of pulmonary hypertension in people with obstructive sleep apnea, a study in mice suggests.| Pulmonary Hypertension News
Researchers developed a tool for predicting the prognosis of people with chronic lung disease-related pulmonary hypertension.| Pulmonary Hypertension News
A larger diameter of the main pulmonary artery predicts poorer outcomes in pulmonary arterial hypertension (PAH) patients, a study found.| Pulmonary Hypertension News
NORD has launched a U.S. study called Living Rare to capture the lived experiences of rare disease patients and identify changing unmet needs.| Pulmonary Hypertension News
The FDA has approved Yutrepia, an inhaled treprostinil formulation, for the treatment of PAH and PH-ILD, two forms of pulmonary hypertension.| Pulmonary Hypertension News
Corsair Pharma is planning a Phase 1 clinical trial of its treprostinil skin patch as a treatment for pulmonary arterial hypertension (PAH).| Pulmonary Hypertension News
Read about the reasons for the development of pulmonary hypertension (PH).| Pulmonary Hypertension News
INOpulse is a portable device by Bellerophon Therapeutics that supplies pulses of nitric oxide, being tested to treat forms of pulmonary hypertension.| Pulmonary Hypertension News
The degree of tricuspid regurgitation (TR), a cardiac abnormality detected in a heart ultrasound, may help predict the outcomes in people with pulmonary arterial hypertension (PAH), a study suggests. Those with more advanced TR were at a higher risk of death. This relationship was seen specifically in the subgroup who would’ve been considered low risk […] The post Heart valve abnormality may signal risk in low-risk PAH patients appeared first on Pulmonary Hypertension News.| Pulmonary Hypertension News – The Web's Daily Resource for PH News
Having pulmonary hypertension (PH) increases the risk of death, both in the short and long term, for individuals undergoing surgery for the heart valve disease aortic stenosis, a new analysis of published studies has found. Noting the older age, generally, of people with aortic stenosis undergoing the procedure, the researchers said it’s possible that an […] The post Risk of death nearly doubles after heart valve surgery for PH patients appeared first on Pulmonary Hypertension News.| Pulmonary Hypertension News – The Web's Daily Resource for PH News
In hypoxic pulmonary hypertension, exosomes derived from stem cells may be a therapy option for preventing abnormal muscle cell growth.| Pulmonary Hypertension News
Early treatment with iNO and pulmonary surfactant reduces the risk of developing BPD associated with PH in preterm infants, a study found.| Pulmonary Hypertension News
Sensydia has completed a development study of its Cardiac Performance System device to detect pulmonary hypertension and heart failure.| Pulmonary Hypertension News
Sensydia reports completing a 5th study supporting algorithms for its Cardiac Performance System to quickly detect pulmonary hypertension.| Pulmonary Hypertension News
Supporters will unite on May 5 to mark World Pulmonary Hypertension Day, with a focus this year on early diagnosis.| Pulmonary Hypertension News
Andrea Lobo is a Science writer at BioNews. She holds a Biology degree and a PhD in Cell Biology/Neurosciences from the University of Coimbra-Portugal, where she studied stroke biology. She was a postdoctoral and senior researcher at the Institute for Research and Innovation in Health in Porto...| Pulmonary Hypertension News
Looking for reliable information on Thromboembolic Pulmonary Hypertension? Find out everything you need to know here.| Pulmonary Hypertension News
Looking for information about pulmonary venous hypertension? PVH's causes, symptoms, diagnosis, and treatments are highlighted here.| Pulmonary Hypertension News
Read about the methods and difficulties to diagnose the lung disease pulmonary hypertension (PH).| Pulmonary Hypertension News
Mutations in certain genes can cause or increase the likelihood of someone developing PAH. This is known as familial or heritable PAH.| Pulmonary Hypertension News
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Increasing irisin, found at lower levels in people with PAH, may help slow disease progression by stopping vascular remodeling, per a study.| Pulmonary Hypertension News
A protein called BMPER found at low levels in models has emerged as a PAH treatment target as it may ease disease progression, per a study.| Pulmonary Hypertension News
A trial of Insmed’s TPIP suggests daily doses of the inhaled dry powder are well tolerated and may improve blood flow in adults with PAH.| Pulmonary Hypertension News
Read about the various types of pulmonary hypertension, and their causes, as classified by the World Health Organization (WHO).| Pulmonary Hypertension News
Platelets tend to cluster in lung blood vessels in people with decompensated pulmonary hypertension, increasing their risk of bleeding, a study says.| Pulmonary Hypertension News
Adding more lines of treatment may reduce the risk of rehospitalization among adults with PAH who are taking only one medication, per a study.| Pulmonary Hypertension News
Low-dose metformin delivered to the pulmonary arteries using lipid-based nanocapsules, safely eased signs of PAH in rats.| Pulmonary Hypertension News
Many patients with heart dysfunction have pulmonary hypertension, more so if they have enlarged hearts or irregular heartbeats, per a study.| Pulmonary Hypertension News
Pulmonary arterial hypertension (PAH) is a rare type of pulmonary hypertension that can be the result of one of several causes, or by no apparent cause. Read more information about PAH here.| Pulmonary Hypertension News
Using a machine-learned algorithm, Corvista's system can accurately diagnose pulmonary hypertension in a noninvasive way, a study shows.| Pulmonary Hypertension News
Some of the common symptoms of pulmonary hypertension include shortness of breath, excessive fatigue, weakness, chest pain, and fainting.| Pulmonary Hypertension News
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Lindsey Shapiro is a science writer for Pulmonary Hypertension News with a PhD in neuroscience. She covers the latest news and information on a variety of pulmonary hypertension topics.| Pulmonary Hypertension News
A combination treatment may improve survival in patients with both pulmonary hypertension and pulmonary fibrosis, a study found.| Pulmonary Hypertension News
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A pivotal study testing Sensydia's noninvasive device, which may help diagnose pulmonary hypertension, enrolled its first participant.| Pulmonary Hypertension News
Cereno Scientific reported a successful meeting with the FDA on the design of a future clinical trial for its PAH therapy candidate CS1.| Pulmonary Hypertension News
Heart failure related to PAH is becoming more common, with patients living fewer years in full health, a trend that’s predicted to continue.| Pulmonary Hypertension News
Pulmonary hypertension (PH) is a chronic and progressive disease associated with high blood pressure in the blood vessels that supply the lungs, known as the pulmonary arteries. Read more about PH here.| Pulmonary Hypertension News
