The results of a network meta-analysis, which evaluated the use of various nutritional supplements for chronic obstructive pulmonary disease (COPD), were published in BMC Pulmonary Medicine. This analysis included 37 randomized and controlled trials, a total of nearly 2,000 participants with COPD, and 21 nutritional interventions. Network analysis allows for a rough comparison between interventions that have not necessarily been compared directly. COPD was defined in these studies as a Forced...| Biotics Research Blog
The Lancet Planetary Health has published a systematic review and meta-analysis of studies examining the association between air pollution and incident dementia. This review was intended to summarize all previous reviews, identify specific gaps in data, and incorporate new primary research. It included data from 32 studies and a pooled population of over 26 million people, evaluating the effect of long-term exposure (defined as one or more years) to single outdoor air pollutants on a subseque...| Biotics Research Blog
Depression is increasingly recognized as a complex, multisystemic condition that extends well beyond neurotransmitter imbalance. Growing evidence reveals a compelling connection between compromised detoxification pathways and the development of depressive symptoms, suggesting that reduced capacity to eliminate toxins can drive systemic inflammation, mitochondrial dysfunction and neurochemical alterations.| blog.bioticsresearch.com
Panvascular disease, or PVD, is an emerging clinical concept referring to a multisite atherosclerotic process that occurs simultaneously or sequentially, affecting multiple vascular beds (e.g., coronary, cerebral, peripheral, etc.). With this approach as its focus, the journal Lipids in Health and Disease published a review which looked at the significance of lipoprotein(a) in PVD.| blog.bioticsresearch.com
The journal Genes (Basel) has published a review of gene-diet interactions in type 2 diabetes mellitus (T2D), describing both the current understanding of genetic risk as well as potential approaches to target genetic risk with nutritional interventions. There is a clear role for hereditary risk in T2D, with first-degree relatives of people with T2D at 3-fold greater risk for developing it themselves. Yet, for most people with T2D, it is the accumulation of many genetic variants that appears ...| blog.bioticsresearch.com
The vagina hosts a dense and distinct microbial ecosystem, comprising approximately 10¹⁰–10¹¹ bacteria. These microbiota, typically dominated by Lactobacillus species, engage in a symbiotic relationship with the host by producing antimicrobial compounds such as lactic acid, hydrogen peroxide, and bacteriocins. These metabolites help maintain an acidic pH and inhibit pathogen colonization, forming a critical component of the innate immune defense.| blog.bioticsresearch.com
The Journal of International Medical Research published a meta-analysis and Mendelian randomization (MR) evaluating the association between glucosamine supplementation and the risk for type 2 diabetes (T2D). Extremely high dose animal studies followed by one previously published human study suggested that glucosamine supplementation might exacerbate insulin resistance when used to treat osteoarthritis.| blog.bioticsresearch.com
An analysis published in the Nutrition Journal suggests that an increased consumption of riboflavin, vitamin B2, is associated with a lower risk of developing osteoporosis. Data was collected from over 4,000 women participating in the National Health and Nutrition Examination Survey (NHANES), a cross-sectional representative study of the U.S. population, including estimates of riboflavin intake as well as dual-energy X-ray absorptiometry (DXA) measurements of femur bone mineral density (BMD).| blog.bioticsresearch.com
A meta-analysis evaluating the efficacy of probiotics/prebiotics among people with cognitive impairment was published in PLoS One. A plausible link occurring via the microbiota-gut-brain axis raises the possibility of benefit with supplementation, and this meta-analysis included 10 randomized and controlled clinical trials to discern the strength of this connection. Combined, this was a total of nearly 800 participants, though all of the included studies were rather small. For example, the la...| Biotics Research Blog
Results from a 2023 randomized, double-blind, placebo-controlled study revealed compelling findings on the impact of pomegranate (Punica granatum) extract on skin health, particularly through the gut-skin axis. Twenty-eight healthy adults aged 25–55 were administered either 75 mg of punicalagin, a potent polyphenol found in pomegranate (PE), or a placebo for four weeks. One of the most remarkable outcomes of PE supplementation was a significant increase in circulating levels of urolithin A ...| Biotics Research Blog
Cauliflower (Brassica oleracea var. Botrytis), a cruciferous (Brassicaceae) vegetable, is packed with robust nutritive and phytochemical content—-including glucosinolates, flavonoids, chlorophyll and phenolics acids, vitamins, minerals, choline, and fiber—exerting widespread health effects.| blog.bioticsresearch.com
Biotics Research - Research and Education Blog - Biotics News and Science Updates| blog.bioticsresearch.com
Mental and emotional stress deplete many of the critical nutrients your body needs to function at its best, even if you have a perfect diet.| blog.bioticsresearch.com
