The journal Frontiers in Microbiologypublished a study that examined the influence of bisphenols on vascular calcification, including data from humans and an animal-based experiment. Given its widely recognized role as an endocrine disruptor, bisphenol A (BPA) has been replaced in many plastic products with other bisphenols, including bisphenol S (BPS), bisphenol F (BPF), and bisphenol AF (BPAF), though they too have been shown to have similar mechanisms of action as well as a magnitude of ef...| Biotics Research Blog
In July 2025, the journal Diabetes Carepublished the results of an observational longitudinal analysis evaluating the ability of a 1-hour oral glucose tolerance test (OGTT) to predict the risk for progression to prediabetes when given to people with normal glucose tolerance. This study included nearly 1,600 participants from the San Antonio Heart Study without diabetes at baseline, who had an initial OGTT and a subsequent OGTT 7.5 years later.| Biotics Research Blog
Pyrethroid pesticides (PYRs) are synthetic insecticides widely used in crops and consumer products, such as residential insecticides, pet sprays and shampoos, lice treatments, and mosquito repellents. A 2025 study published in Ecotoxicology and Environmental Safety reported on the relationship between exposure to PYRs and neurodevelopment between the ages of 1 and 2. The final analysis included 305 children from a rural area in China participating in a prospective birth cohort study who under...| blog.bioticsresearch.com
Is there a connection between vitamin B3 and liver health? Research suggests that there is. We are seeing studies suggesting that dietary intake of vitamin B3 may play a role in helping with the risk for metabolic dysfunction-associated steatotic liver disease (MASLD), as well as overall mortality among people with this condition. A number of possible mechanisms have been identified supporting this association.| Biotics Research Blog
BMJ published the results of a multi-center randomized and placebo-controlled double-blind phase 3 trial evaluating the efficacy of oral methylcobalamin (vitamin B12) to help prevent hand-foot syndrome among women receiving capecitabine treatment for human epidermal growth factor receptor 2 (HER2) negative early breast cancer. A range of 29–73% of women receiving treatment with capecitabine experience hand-foot syndrome, characterized by redness, pain, swelling, and dysesthesia in the palms...| blog.bioticsresearch.com
Researchers from the University of Turin published the results of a prospective, randomized, and controlled trial evaluating the use of L-carnitine and selenium when combined with standard therapy for Graves’ disease, an autoimmune disorder that affects the thyroid gland. This study follows a previously published pilot study, which found that 500 mg of L-carnitine in combination with 83 mcg selenium (as selenomethionine) taken daily for one month could improve quality of life and symptoms a...| Biotics Research Blog
Trihalomethanes The results of a cohort study published in JAMA Network Open show the effect of trihalomethanes in community drinking water on the risk of chronic kidney disease (CKD). Trihalomethanes (THMs) are one of several unintended byproducts of chlorination, and include chloroform and three brominated compounds (bromodichloromethane, dibromochloromethane, and bromoform), with the latter more common in coastal and saltwater regions. Exposure to THMs has already been established as a r...| Biotics Research Blog
Findings from a 2023 study published in The American Journal of Physiology – Cell Physiology underscore that skeletal muscle is strongly dependent on mitochondrial integrity and the regulation of cellular senescence. This relationship becomes evident when either system is disrupted, as senescent cell accumulation can impede mitochondrial function, compromising muscle adaptability and systemic resilience.| blog.bioticsresearch.com
The journal Alzheimer’s & Dementiapublished the results of a lipidomics study, which found significant differences in plasma lipids associated with Alzheimer’s disease (AD), but only among women. This study was a post hoc analysis of data from two cohorts, the AddNeuroMed and Dementia Case Register cohorts, both conducted among European populations. A total of 841 participants were involved, including 306 diagnosed with AD, 165 with mild cognitive impairment (MCI), and 370 cognitively hea...| Biotics Research Blog
A study published in Cell Reports Medicine examined the role of homocysteine in glaucoma development and progression, including models of glaucoma, clinical data, and Mendelian randomization, and suggests that several B vitamins have a promising role as neuroprotective agents. Homocysteine elevations have been linked to a number of neurodegenerative diseases, but it has been difficult to determine if it is a causative agent or a biomarker for other pathological processes (or nutrient deficien...| blog.bioticsresearch.com
Depression is increasingly recognized as a complex, multisystemic condition that extends well beyond neurotransmitter imbalance. Growing evidence reveals a compelling connection between compromised detoxification pathways and the development of depressive symptoms, suggesting that reduced capacity to eliminate toxins can drive systemic inflammation, mitochondrial dysfunction and neurochemical alterations.| blog.bioticsresearch.com
Panvascular disease, or PVD, is an emerging clinical concept referring to a multisite atherosclerotic process that occurs simultaneously or sequentially, affecting multiple vascular beds (e.g., coronary, cerebral, peripheral, etc.). With this approach as its focus, the journal Lipids in Health and Disease published a review which looked at the significance of lipoprotein(a) in PVD.| blog.bioticsresearch.com
