Why are Derek Thompson and Andrew Huberman certain the obesity epidemic is as simple as elementary physics?| uncertaintyprinciples.substack.com
Eating too much is not a physiological condition but a behavior. If that’s what causes obesity, then how is this not a behavioral problem?| Uncertainty Principles
The recent obsession with ultra-processed foods spotlights a world of industry-related issues, while rendering sugar and refined grains almost benign in the process.| uncertaintyprinciples.substack.com
If the journal editors can't accept uncertainty in the science of weight regulation, the physicians never will.| uncertaintyprinciples.substack.com
What do you do when the latest clinical trial contradicts the core assumption of UPF science? How about accentuate the positive and eliminate the negative?| uncertaintyprinciples.substack.com
The latest nutrition news tells us more about the state of the science (and the reporting) than it does what we need to know.| Uncertainty Principles
What a pair of experiments--one a thought experiment, one a century old--tell us about the illogic of overeating.| Uncertainty Principles
Nutrition dogma habitually ignores the past. Paying attention, after all, can be terribly inconvenient.| Uncertainty Principles
With all the interest in the dangers and addictive nature of ultra-processed foods, can we start, please, with the right questions and the right experiment?| Uncertainty Principles
If you want to demonstrate that a low-fat diet is better than a ketogenic diet (or that ultra-processed food makes us overeat), these critical design flaws will help.| Uncertainty Principles
A "top" nutrition researcher exits, followed by two damning articles challenging his studies and claiming that a flagship $170 million NIH initiative is "designed to fail."| Uncertainty Principles
A new study once again suggests something far more profound than eating less.| Uncertainty Principles
Some large proportion of GLP-1 drug users will discontinue use eventually. What do they eat then to maintain their weight loss?| Uncertainty Principles
That depends on whether we believe the hypotheses or believe the tests: Part 3 of a rules of evidence controversy.| Uncertainty Principles
The latest from our friends in nutritional epidemiology. Should we be grateful? Part 2 of a rules of evidence controversy.| Uncertainty Principles
Ozempic and Wegovy will curb your appetite. Is that why you lose weight?| Uncertainty Principles
When contemplating the ideal therapy for chronic conditions like obesity and diabetes, shouldn't this always be the context?| Uncertainty Principles
After a lengthy run of wonderful publicity from the media, Dan Buettner and his blue zones run into a storm of criticism. A good thing? Yes, but it misses the point.| Uncertainty Principles
Ultra-processed foods are the hottest subject in nutrition. Is it too much to ask the journalists writing about them (and the researchers studying them) to think critically?| uncertaintyprinciples.substack.com
Watch carefully and you can see the sleight of hand built into the creation of the Dietary Guidelines for Americans (courtesy of the Harvard School of Public Health)| uncertaintyprinciples.substack.com
What can we learn about aging well from the "potential downsides" of living hungry?| uncertaintyprinciples.substack.com