Background The clinical features of neuromyelitis optica spectrum disorder (NMOSD) predominantly include optic neuritis and myelitis, among other symptoms. A greater level of disability during the acute phase typically suggests an unfavorable prognosis. Nevertheless, the clinical biomarkers that impact the severity of disability in NMOSD remain unclear. Methods We analyzed 41 NMOSD patients and 41 normal controls to identify biomarkers associated with the disease. NMOSD patients were categori...| BioMed Central
BMC Neurology is an open access, peer-reviewed journal that considers articles on all aspects of the prevention, diagnosis and management of neurological ...| BioMed Central
Background Myasthenia gravis (MG) is an autoimmune disorder of the neuromuscular junction. Increasing evidence has suggested inflammation is involved in the pathogenesis of MG, but whether it is the cause or a downstream effect remains unclear. In this study, a two-sample Mendelian randomization (TSMR) analysis was performed to explore the causal relationship between 91 circulating inflammatory cytokines and MG. Method In this study, the data of 91 circulating inflammatory cytokines from 4824...| BioMed Central