How Scientific Incentives Stalled the Fight Against Antibiotic Resistance, and How We Can Fix It
Peptide-DB: A Million-Peptide Database to Accelerate Science| Macroscience
Peptide-DB: A Million-Peptide Database to Accelerate Science| Macroscience
IN THIS EPISODE: Professor Heidi Williams, Professor Paul Niehaus, and Matt Clancy walk through academic, non-profit and private sector paths to research, the importance of your surroundings, and how you can find good use-inspired questions.| Macroscience
IN THIS EPISODE: Journalist Derek Thompson and economist Eli Dourado investigate the bottlenecks standing in the way of the invention vs.| Macroscience
IN THIS EPISODE: Journalist Dylan Matthews leads a conversation with Open Philanthropy CEO Alexander Berger, Professor Tyler Cowen, and IFP Co-CEO Caleb Watney. Together, they explore the relationship between effective, robust scientific institutions and notions of political legitimacy.| Macroscience
IN THIS EPISODE: Journalist Dylan Matthews sits down with Professor Tyler Cowen, Matt Clancy, and Jacob Trefethen to discuss whether there are tensions between accelerating science and safety.| Macroscience
Listen now (58 mins) | IN THIS EPISODE: Professor Heidi Williams, Professor Paul Niehaus, Emily Oehlsen, and Jim Savage dive in on a practical “how-to” for experimentation and evaluation in metascience.| Macroscience
IN THIS EPISODE: Journalist Kelsey Piper interviews Convergent Research CEO Adam Marblestone and Professor Paul Niehaus on the inputs to scientific production.| Macroscience
One of the questions we get most frequently at IFP is: “Metascience seems like a really cool area of research.| Macroscience
IN THIS EPISODE: Journalist Dylan Matthews sits down with economist Heidi Williams and IFP co-founder Caleb Watney to set the scene.| Macroscience
Unpacking the aesthetics and ideology of progress| Macroscience
A newsletter about macroscientific theory, policy, and strategy. Click to read Macroscience, by Tim Hwang, a Substack publication with thousands of subscribers.| www.macroscience.org
There’s a reason why Oppenheimer will focus on the Manhattan Project, and not the bopping quantum physics scene in Göttingen that gave a young Robert Oppenheimer his start.| www.macroscience.org
IN THIS EPISODE: Stripe Press’s Tamara Winter talks through the broad range of scientific funding institutions with guests Professor Tyler Cowen, Arc Institute Co-Founder Professor Patrick Hsu, and Convergent Research CEO Adam Marblestone. They pay special attention to the renaissance in new, exploratory scientific funding models.| www.macroscience.org
Listen now (79 mins) | IN THIS EPISODE: OpenPhil CEO Alexander Berger interviews economist Matt Clancy and Stripe co-founder Patrick Collison to talk about whether science itself is slowing down, one of the key motivating concerns in metascience.| www.macroscience.org
Scholarly fields – economics, physics, computer science – are the basic units for thinking about metascience.| www.macroscience.org
There’s a tension between two basic metascientific instincts.| www.macroscience.org
A few weeks back, I wrote about negative metascience. While “traditional” metascience is about studying what makes science work well, or faster, negative metascience is the idea that there’s value in attempting to defend scientific processes and institutions against inhibitors of progress. While we need a traditional, positive metascience to improve our science, we also need a better understanding of science’s failure modes. That’s what negative metascience is for.| www.macroscience.org
As part of my work at IFP, I’m helping to co-organize the Bottlenecks Summit, which will take place in September in collaboration with the Abundance Institute and the Foundation for American Innovation. The summit will be focused on bringing together a wide set of “thinkers, builders, creators and policy entrepreneurs working to overcome bottlenecks to human progress and abundance.”| www.macroscience.org
It’s not every day that philosophy of science ends up as the main character of a social media beef.| www.macroscience.org
I was inspired recently by an offhand joke from Jordan Dworkin that a major new cause area for the progress community could be metaparascience — the science of parascience.| www.macroscience.org
Discussions about metascience are frequently not about science, but about money.| www.macroscience.org
Science is a dynamic system.| www.macroscience.org
If you’re not already familiar (and, frankly, are the kind of person who is weird enough to be subscribed to Macroscience), I highly recommend that you immediately stop what you’re doing and visit the Wikipedia page for “long-term experiment”.| www.macroscience.org
